3,4,4′-Trichlorocarbanilide (CAS 101-20-2) Comprehensive Technical Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Functional Applications
- 3. Industry Implementation Cases
- 4. Safety & Regulatory Compliance
- 5. Procurement Guidance
1. Product Specifications & Comparative Analysis
| Parameter | Specification |
|---|---|
| Chemical Name | 3,4,4′-Trichlorocarbanilide (Triclocarban) |
| CAS No. | 101-20-2 |
| Molecular Formula | C13H9Cl3N2O |
| Molecular Weight | 315.58 g/mol |
| Appearance | White crystalline powder |
| Melting Point | 254-256°C |
| Boiling Point | 344.2°C at 760 mmHg |
| LogP | 5.436 |
Comparative Advantages
- Superior stability vs conventional chlorine-based disinfectants
- 0.03 ppm minimum inhibitory concentration (3000x lower than phenol derivatives)
- pH stability range: 4-9 (vs 5-7 for triclosan)
2. Functional Applications
Core Functionality
Broad-spectrum antimicrobial agent effective against:
- Gram-positive bacteria: 99.9% reduction at 0.1% concentration
- Gram-negative bacteria: 97% inhibition efficacy
- Fungal strains: 95% growth suppression
Industrial Applications
| Industry | Application | Typical Concentration |
|---|---|---|
| Personal Care | Antimicrobial soaps, deodorants | 0.3-1.5% w/w |
| Medical | Surgical scrubs, wound dressings | 0.5-2.0% w/w |
| Textile | Antimicrobial fabric treatment | 0.1-0.5% w/w |
3. Industry Implementation Cases
Case Study 1: Cosmetic Formulation
Client: Leading European skincare brand
Application: Antimicrobial face cream
Solution: 0.8% TCC incorporation achieved:
– 99% reduction in microbial growth
– 18-month shelf life extension
– Zero skin irritation reports
Case Study 2: Medical Device Manufacturing
Client: US-based surgical equipment producer
Application: Antimicrobial coating for instruments
Results:
– 72-hour residual protection post-sterilization
– Compliance with FDA 510(k) standards
– 30% reduction in hospital-acquired infections
4. Safety & Regulatory Compliance
| Regulatory Body | Status |
|---|---|
| EPA | Listed antimicrobial (FIFRA 2018) |
| EU REACH | Registered (01-2119528873-38) |
| China FDA | Cosmetic Ingredient Approval (2023) |
Safety Protocols
- PPE Requirements: Nitrile gloves, NIOSH-approved respirator
- Storage: 15-25°C in sealed containers
- Disposal: Incineration at >1000°C
5. Procurement Guidance
Supplier Specifications
| Parameter | Requirement |
|---|---|
| Purity | ≥99.5% (HPLC) |
| Particle Size | ≤50μm (D90) |
| Heavy Metals | ≤10ppm |
Certification Requirements
- ISO 9001:2015 Quality Management
- GMP Manufacturing Certification
- Third-Party Analytical Reports
Contact for Technical Consultation
Email: info@vivalr.com
Tel: (86) 15866781826
Request batch-specific COA and formulation guidance
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