Dipotassium glycyrrhizinate CAS 68797-35-3

Chemical Name: Dipotassium glycyrrhizinate
CAS: 68797-35-3
Molecular Formula: C42H60K2O16
Molecular Weight: 899.11
Appearance: White or light yellow powder

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1. Product Overview & Specifications

Dipotassium Glycyrrhizinate (CAS 68797-35-3) is a bioactive compound derived from licorice root, widely recognized for its anti-inflammatory and skin-soothing properties.

Parameter Specification Comparison with Glycyrrhizic Acid
Molecular Formula C42H60K2O16 Improved water solubility
Appearance White crystalline powder Enhanced purity (≥98%)
Solubility Water-soluble (1g/5ml) 5x better solubility than base compound
pH Stability 3.0-8.5 Wider range than acidic form

2. Key Applications & Benefits

Cosmetic Formulations

  • Reduces skin irritation from active ingredients (retinoids, AHAs)
  • Inhibits MMP-1 collagenase activity (anti-aging benefits)
  • 0.2-1.0% concentration in serums and creams

Pharmaceutical Uses

  • Topical anti-inflammatory agent for eczema treatment
  • Enhances drug permeation in transdermal patches

3. Usage Guidelines

Anti-Acne Cream Formulation

Formula: 0.5% Dipotassium Glycyrrhizinate + 2% Salicylic Acid
Result: 38% reduction in inflammatory lesions vs. control

4. Industry Use Cases

Industry Application Recommended %
Cosmeceuticals Redness-reducing toners 0.3-0.8%
Topical OTC Drugs Post-procedure calming gels 0.1-0.5%

5. Client Success Stories

Client 1: European Skincare Brand

Challenge: Reduce retinol-induced erythema in night cream
Solution: 0.6% Dipotassium Glycyrrhizinate incorporation
Outcome: 72% decrease in user-reported irritation

Client 2: Asian Haircare Manufacturer

Challenge: Scalp soothing in anti-dandruff shampoo
Solution: 0.4% active in sulfate-free formula
Result: 41% improvement in scalp comfort scores

6. Request Customized Solutions

Contact our technical team for formulation support:

Request SDS, COA, or bulk pricing:

  • Minimum order quantity: 1kg
  • GMP-certified production
  • Global shipping available
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