Table of Contents
1. Product Overview & Specifications
Dipotassium Glycyrrhizinate (CAS 68797-35-3) is a bioactive compound derived from licorice root, widely recognized for its anti-inflammatory and skin-soothing properties.
| Parameter | Specification | Comparison with Glycyrrhizic Acid |
|---|---|---|
| Molecular Formula | C42H60K2O16 | Improved water solubility |
| Appearance | White crystalline powder | Enhanced purity (≥98%) |
| Solubility | Water-soluble (1g/5ml) | 5x better solubility than base compound |
| pH Stability | 3.0-8.5 | Wider range than acidic form |
2. Key Applications & Benefits
Cosmetic Formulations
- Reduces skin irritation from active ingredients (retinoids, AHAs)
- Inhibits MMP-1 collagenase activity (anti-aging benefits)
- 0.2-1.0% concentration in serums and creams
Pharmaceutical Uses
- Topical anti-inflammatory agent for eczema treatment
- Enhances drug permeation in transdermal patches
3. Usage Guidelines
Anti-Acne Cream Formulation
Formula: 0.5% Dipotassium Glycyrrhizinate + 2% Salicylic Acid
Result: 38% reduction in inflammatory lesions vs. control
4. Industry Use Cases
Anti-Acne Cream Formulation
Formula: 0.5% Dipotassium Glycyrrhizinate + 2% Salicylic Acid
Result: 38% reduction in inflammatory lesions vs. control
| Industry | Application | Recommended % |
|---|---|---|
| Cosmeceuticals | Redness-reducing toners | 0.3-0.8% |
| Topical OTC Drugs | Post-procedure calming gels | 0.1-0.5% |
5. Client Success Stories
Client 1: European Skincare Brand
Challenge: Reduce retinol-induced erythema in night cream
Solution: 0.6% Dipotassium Glycyrrhizinate incorporation
Outcome: 72% decrease in user-reported irritation
Client 2: Asian Haircare Manufacturer
Challenge: Scalp soothing in anti-dandruff shampoo
Solution: 0.4% active in sulfate-free formula
Result: 41% improvement in scalp comfort scores
6. Request Customized Solutions
Contact our technical team for formulation support:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request SDS, COA, or bulk pricing:
- Minimum order quantity: 1kg
- GMP-certified production
- Global shipping available



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