Salicylic acid CAS 69-72-7

Appearance: White or off-white powder for industry grade; Shallow pink to brown crystalline powder for medicinal grade
Other Name: 2-Hydroxybenzoic Acid; Salicylic acid EP
Assay: 99%
Packing: 25kg/bag
Capacity: 10000MT/year
Sample: Available

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Salicylic Acid (CAS 69-72-7): Comprehensive Product Guide

1. Product Specifications & Comparisons

Parameter Pharmaceutical Grade Industrial Grade Sublimed Grade
CAS Number 69-72-7
Molecular Formula C7H6O3
Molecular Weight 138.12 g/mol
Purity ≥99% ≥98% ≥99.5%
Melting Point 158-161°C 155-160°C 159-162°C
Water Solubility (20°C) 1.8 g/L 1.6 g/L 1.9 g/L

2. Key Applications

Pharmaceutical Industry

  • COX-2 inhibitor for anti-inflammatory formulations
  • Active component in topical keratolytic agents
  • Intermediate in aspirin production

Cosmeceutical Formulations

  • Acne treatment products (0.5-2% concentration)
  • Chemical exfoliants in anti-aging serums
  • Dandruff control in shampoos

Agricultural Applications

  • Plant defense signal molecule
  • Systemic acquired resistance (SAR) inducer
  • Thermogenesis regulator in thermogenic plants

3. Usage Guidelines

Pharmaceutical Preparation

Recommended dosage: 1-5% in topical formulations. For COX-2 inhibition, maintain concentration below 20mg/mL to avoid NF-κB activation interference.

Cosmetic Integration

Optimal pH range: 3.0-3.5. Combine with ethanol (1M concentration) for enhanced solubility. Avoid simultaneous use with strong oxidizing agents.

Agricultural Implementation

Apply 0.1-1.0 mM solution through foliar spray. Maintain storage at ambient temperature with light-sensitive packaging.

4. Industry Case Studies

Dermatological Solution Development

A leading skincare brand achieved 89% efficacy in acne reduction using 2% salicylic acid combined with zinc pyrithione in pH-controlled emulsion.

Pharmaceutical Synthesis

GMP facility optimized aspirin production yield by 18% through precise control of salicylic acid particle size (50-75μm) and reaction temperature.

5. Client Success Stories

Xi’an Heguan Biotechnology

Annual consumption: 25 metric tons. Application: Cosmetic-grade formulations. Result: 40% reduction in production costs through optimized purification processes.

Beijing BioLab Scientific

Research use: 500kg/year. Achievement: Developed novel nanoparticle delivery system enhancing dermal absorption by 300%.

Wuhan Yuancheng Technology

Industrial-scale production: 100MT/month. Innovation: Implemented closed-loop sublimation system achieving 99.9% purity consistently.

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