Table of Contents
- Product Overview
- Specification Comparison
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Quotation
Pentafluorophenol (CAS 771-61-9) Technical Overview
Basic Properties
| Parameter | Value |
|---|---|
| CAS Number | 771-61-9 |
| Molecular Formula | C6HF5O |
| Molecular Weight | 184.06 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥99% (HPLC) |
| Melting Point | 35-38°C |
| Boiling Point | 205-207°C |
| Flash Point | 93°C |
Comparative Analysis with Fluorophenol Derivatives
| Compound | CAS | Reactivity | Thermal Stability | Applications |
|---|---|---|---|---|
| Pentafluorophenol | 771-61-9 | High | Excellent | Pharmaceutical intermediates |
| Tetrafluorophenol | 771-40-4 | Moderate | Good | Polymer modification |
| Trifluorophenol | 827-52-1 | Low | Fair | Agrochemical synthesis |
Industrial Applications of Pentafluorophenol
Pharmaceutical Manufacturing
Critical intermediate for HIV protease inhibitors and anticancer drugs. Enables precise fluorine substitution in molecular design.
Organic Synthesis
Preferred activating agent for:
– Peptide coupling reactions
– Esterification catalysts
– Nucleophilic substitution reactions
Material Science
Key component in:
– Liquid crystal polymers
– Fluorinated epoxy resins
– High-performance coatings
Operational Guidelines
Handling Protocols
| Parameter | Requirement |
|---|---|
| Storage Temperature | 2-8°C (under inert gas) |
| Shelf Life | 24 months in original packaging |
| Reaction Solvents | DCM, THF, DMF (anhydrous) |
| Safety Equipment | Chemical goggles, PTFE gloves |
Documented Success Cases
Case 1: European Pharma Company
Challenge: Improve yield in antiviral drug intermediate synthesis
Solution: Implemented pentafluorophenol-mediated coupling
Result: 22% yield increase, 99.5% purity achieved
Case 2: Asian Material Supplier
Challenge: Develop heat-resistant fluoropolymer coating
Solution: Used as crosslinking agent in resin formulation
Result: 300°C thermal stability, 50% faster curing
Request Professional Support
Customized solutions available for:
– Bulk ordering (100kg+ quantities)
– Technical documentation support
– Regulatory compliance guidance
Contact our chemical experts:
Email: info@vivalr.com
Tel: (86) 15866781826



评论
目前还没有评论。