Table of Contents
Glycerophosphoric Acid (CAS 57-03-4) Overview
A versatile biochemical intermediate widely used in pharmaceutical formulations, nutraceuticals, and industrial applications. Key identifiers:
| Parameter | Value |
|---|---|
| CAS Number | 57-03-4 |
| Molecular Formula | C3H9O6P |
| Molecular Weight | 172.07 g/mol |
| Appearance | Colorless viscous liquid |
| Purity Grade | Technical (85-90%), Pharmaceutical (>98%) |
Technical Specifications Comparison
| Grade | Purity | Applications | Storage |
|---|---|---|---|
| Technical | 85-90% | Industrial processes, Detergents | 2-8°C |
| Pharmaceutical | >98% | Drug formulations, Supplements | -20°C |
| Food Grade | >99% | Food additives, Emulsifiers | 4-25°C |
Industrial & Commercial Applications
Pharmaceutical Uses
- Calcium absorption enhancer in osteoporosis medications
- Cell signaling intermediate in metabolic drugs
- Excipient for lipid-based drug delivery systems
Food & Nutrition
- Emulsifier in dairy products (E number pending approval)
- Bioavailable mineral carrier in nutritional supplements
Cosmetic Applications
- pH balancer in skincare formulations
- Moisturizing agent in hair care products
Optimal Usage Parameters
| Application | Concentration | Temperature Range | Compatibility |
|---|---|---|---|
| Oral Supplements | 50-200mg/dose | RT | Avoid strong oxidizers |
| Topical Formulations | 0.5-2% w/w | 15-30°C | Compatible with most emulsifiers |
| Industrial Processes | 5-15% solution | 40-60°C | Stainless steel equipment required |
Documented Use Cases
Case Study 1: European Pharma Manufacturer
- Client Profile: Top 10 osteoporosis drug producer
- Challenge: Improve calcium bioavailability in tablet formulation
- Solution: 1.8% glycerophosphoric acid additive
- Result: 37% increase in calcium absorption rates
Case Study 2: Asian Nutraceutical Company
- Client Profile: Sports nutrition supplement developer
- Challenge: Stabilize mineral suspension in liquid products
- Solution: 0.75% glycerophosphoric acid complex
- Result: 12-month shelf stability achieved
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