5-Amino-2,4,6-Triiodoisophthalic acid CAS 35453-19-1

Chemical Name: 5-Amino-2,4,6-triiodoisophthalic acid
Synonyms: 5-Amino-2,4,6-iodoisophthalic acid; Aminoiodoisophthalicacid
CAS No.: 35453-19-1
Molecular Formula: C8H4I3NO4
Molecular weight: 558.84
Appearance: Yellowish powder
Assay: 99%min

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5-Amino-2,4,6-Triiodoisophthalic Acid (CAS 35453-19-1) User Guide

1. Product Overview & Specifications

CAS No.: 35453-19-1
Molecular Formula: C8H4I3NO4
Molecular Weight: 626.83 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)

Comparative Analysis

Parameter This Product Generic Triiodobenzene Derivatives
Iodine Content 60.7% 55-58%
Solubility Soluble in DMSO, DMF Limited solubility

2. Key Applications

Widely used as:

  • Critical intermediate in X-ray contrast agents (e.g., Iopamidol, Iohexol)
  • Building block for MRI contrast media
  • High-density reagent in polymer chemistry

3. Usage Scenarios

  1. Pharmaceutical Synthesis: React with epoxides to create non-ionic contrast molecules
  2. Quality Control: HPLC analysis with mobile phase acetonitrile/water (70:30)
  3. Storage: Maintain at 2-8°C in amber glass containers

4. Customer Case Studies

Case 1: PharmaHealth Inc. (USA)

Challenge: Needed high-purity intermediate for Iohexol production
Solution: Used 2.5kg batch with 99.2% purity
Result: Achieved 92% yield in final API synthesis

Case 2: ResearchLab Co., Ltd. (Germany)

Challenge: Develop low-osmolarity contrast agent
Solution: Custom synthesis with modified carboxyl groups
Result: Reduced osmolarity by 40% vs. commercial products

5. Contact for Inquiries

Request custom synthesis, bulk pricing, or COA:
Email: info@vivalr.com
Phone: (86) 15866781826

➤ ISO-certified production ➤ Technical documentation support ➤ Global shipping

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