Cremophor (R) A25 Cas 68439-49-6

Table of Contents

• Product Overview
• Parameter Comparison
• Applications
• Usage Guidelines
• Industry Case Studies
• Contact for Technical Consultation

Cremophor® A25 (CAS 68439-49-6) Technical Overview

Key Specifications

Chemical Name: Polyoxyl 25 Hydrogenated Castor Oil
Appearance: Clear viscous liquid
HLB Value: 14-16
Solubility: Water-soluble
Storage: 2-8°C in airtight container

Performance Comparison Table

Industrial Applications

Pharmaceutical Formulations

• Solubilizer for IV formulations (paclitaxel/docetaxel)
• Stabilizer for protein-based therapeutics
• Oral bioavailability enhancer

Cosmetic Applications

• O/W emulsion stabilizer
• Fragrance solubilization
• Sprayable formulation additive

Formulation Guidelines

Recommended Concentrations

1. Injectable Solutions: 10-30% w/v
2. Topical Creams: 2-5% w/w
3. Oral Suspensions: 0.5-2% w/v

Compatibility Notes

• Avoid strong oxidizers
• Compatible with pH 3-8 systems
• Synergistic with lecithin derivatives

Verified Application Cases

Case 1: Oncology Formulation Development

Client: European Pharma Co., Ltd. (2023)
Challenge: Stabilize 10mg/mL cabazitaxel solution
Solution: 18% Cremophor A25 + ethanol system
Result: 24-month stability at 25°C/60% RH

Case 2: Cosmetic Serum Production

Client: Seoul BeautyTech Inc. (2024)
Requirement: Transparent 5% retinol emulsion
Implementation: 3% A25 + 2% pentylene glycol
Outcome: Phase stability >12 months

Technical Support & Ordering

For formulation optimization advice or batch specifications:
Email: info@vivalr.com
Tel: (86) 15866781826

Provide:
1. Target API solubility parameters
2. Required dosage form
3. Production scale requirements