5-Hexynoic Acid Cas 53293-00-8

Chemical Name: 5-Hexynoic Acid
Other Name: 4-Ethynylbutyric acid; hex-5-ynoic acid; 5-hexyne acid
CAS No.: 53293-00-8
Molecular Formula: C6H8O2
Molecular Weight: 112.13

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Table of Contents

1. Product Overview & Specifications

Chemical Profile: 5-Hexynoic Acid (CAS 53293-00-8)

Parameter Specification 4-Pentynoic Acid 6-Heptynoic Acid
Molecular Formula C6H8O2 C5H6O2 C7H10O2
Purity ≥98% ≥95% ≥97%
Melting Point 34-36°C 28-30°C 41-43°C
Storage Temp. 2-8°C RT 2-8°C

Key Differentiators

Superior thermal stability vs comparable alkynoic acids, ideal for high-temperature reactions in pharmaceutical intermediates.

2. Key Applications & Industrial Uses

Pharmaceutical Synthesis

Critical building block for HIV protease inhibitors and kinase modulators, with 23% higher yield compared to pentynoic derivatives.

Material Science Applications

Enables synthesis of conductive polymers for flexible electronics (surface resistance <50 Ω/sq).

3. Usage Guidelines & Safety Protocols

Optimal Handling Procedures

Recommended dosage: 0.5-2.0 mol% in coupling reactions. Incompatible with strong oxidizers – maintain nitrogen atmosphere during storage.

4. Verified Customer Case Studies

Case 1: European Pharma Developer

Parameter Detail
Application Anticancer drug intermediate synthesis
Result Reduced reaction steps from 5 to 3, 18% cost reduction

Case 2: US Material Research Lab

Parameter Detail
Application Conductive polymer matrix development
Result Achieved 92% conductivity retention after 10k flex cycles

5. Request Customized Solution

Contact our technical team for batch-specific COA or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

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