tetraphenylphosphonium chloride cas 2001-45-8

Product Name: Tetraphenylphosphonium chloride
CAS: 2001-45-8
Molecular Formula:C24H20ClP
Molecular weight:374.84
Appearance: White to beige Crystalline powder
Assay: 98%min

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Tetraphenylphosphonium Chloride (CAS 2001-45-8): Comprehensive User Guide

1. Product Overview & Specifications

Tetraphenylphosphonium chloride (CAS 2001-45-8) is a quaternary phosphonium salt with the chemical formula C24H20ClP. This organophosphorus compound is widely used as:

  • Phase-transfer catalyst in organic synthesis
  • Ion-pairing agent in analytical chemistry
  • Precursor for specialty chemicals

Technical Specifications

Parameter Specification
Molecular Weight 374.84 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC grade available)
Solubility Water: 50 mg/mL, soluble in polar organic solvents

2. Key Applications & Use Cases

2.1 Organic Synthesis Applications

As a phase-transfer catalyst (PTC), it enables reactions between hydrophilic and hydrophobic reactants in:

  • Nucleophilic substitution reactions
  • Polymerization processes
  • Asymmetric synthesis

2.2 Analytical Chemistry Uses

In HPLC applications, it serves as:

  • Ion-pair reagent for acidic analytes
  • Mobile phase additive for improved separation

3. Performance Comparison

Property TPPCl TPPBr TBAHS
Thermal Stability Up to 250°C 220°C 180°C
Solubility in H2O Moderate High Excellent
Catalytic Efficiency ★★★★☆ ★★★☆☆ ★★☆☆☆

4. Industry Application Scenarios

Pharmaceutical Manufacturing

Used in production of:

  • Antiviral drug intermediates
  • Anticancer compound synthesis

Electronic Materials

Key component for:

  • Conductive polymer synthesis
  • OLED material preparation

5. Verified Customer Case Studies

Case 1: Specialty Chemical Producer (Germany)

Challenge: Required high-purity PTC for sensitive fluorination reactions
Solution: Implemented our HPLC-grade TPPCl (99.5% purity)
Result: 18% yield improvement with 99% enantiomeric excess

Case 2: Asian Pharmaceutical Company

Challenge: Needed thermally stable catalyst for continuous flow synthesis
Solution: Customized TPPCl formulation with enhanced stability
Result: Achieved 72-hour continuous operation at 200°C

6. Technical Support & Inquiry

Our technical team provides:

  • Custom purity formulations (98%-99.9%)
  • Bulk quantities (up to 500kg/batch)
  • Regulatory documentation support

Contact our experts:
Email: info@vivalr.com
Phone: (86) 15866781826

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