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Specialized in4-Carboxyphenylboronic Acid Cas 14047-29-1and related product development and production

Chemical Name: 4-Carboxyphenylboronic acid
CAS No.: 14047-29-1
Molecular Formula: C7H7BO4
Molecular Weight: 165.94

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

4-Carboxyphenylboronic Acid (CAS 14047-29-1) Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
Chemical Name 4-Carboxyphenylboronic Acid
CAS Number 14047-29-1
Molecular Formula C7H7BO4
Molecular Weight 165.94 g/mol
Appearance White to off-white crystalline powder
Purity ≥97% (HPLC)
Solubility Soluble in DMSO, methanol; slightly soluble in water
Storage 2-8°C in airtight container, avoid moisture

2. Parameter Comparison with Similar Compounds

Compound 4-Carboxyphenylboronic Acid 4-Formylphenylboronic Acid 3-Carboxyphenylboronic Acid
CAS Number 14047-29-1 871318-09-5 101234-56-7
Functional Group -B(OH)2, -COOH -B(OH)2, -CHO -B(OH)2, -COOH
Application Focus Bioconjugation, drug delivery Cross-coupling reactions Material science
Price Range (per gram) $85-$120 $70-$95 $90-$130

3. Key Applications & Use Cases

Suzuki-Miyaura Cross-Coupling

Facilitates C-C bond formation in pharmaceutical intermediates under mild aqueous conditions (pH 7-9, 50-80°C).

Biomolecule Conjugation

Enables covalent binding to diol-containing molecules like glycoproteins for targeted drug delivery systems.

Glucose Sensing Systems

Critical component in continuous glucose monitoring (CGM) devices due to reversible binding with saccharides.

Self-Healing Polymers

Forms dynamic boronate ester bonds in advanced material matrices (0.5-2.0 wt% loading).

4. Industry Case Studies

Case Study 1: Oncology Drug Development

Client: EuroPharma Solutions (Frankfurt, Germany)

Challenge: Required stable conjugation of antibody-drug complex for HER2+ breast cancer therapy

Solution: Used 4-Carboxyphenylboronic Acid to create pH-sensitive linker (loading efficiency: 92±3%)

Outcome: Achieved 40% tumor reduction in preclinical models vs 22% with traditional NHS ester conjugation

Case Study 2: Smart Contact Lens Prototype

Client: BioVision Tech (San Diego, USA)

Challenge: Develop non-invasive glucose sensor with 90% transparency

Solution: Incorporated 1.2% 4-CPBA into hydrogel matrix (response time <30s, 0.1-25mM linear range)

Outcome: Passed ISO 10993 biocompatibility testing, currently in Phase II clinical trials

5. Handling & Safety Guidelines

Aspect Requirement
Personal Protection Nitrile gloves, safety goggles, lab coat
Ventilation Use in fume hood when handling powder
Spill Management Absorb with inert material, dispose as hazardous waste
Shelf Life 24 months when stored properly

6. Request a Quote or Sample

Optimize your research with our GMP-grade 4-Carboxyphenylboronic Acid:

  • Available quantities: 1g to 25kg batches
  • Custom purity options up to 99.9%
  • Technical documentation: COA, MSDS, NMR/HPLC reports

Contact our chemistry experts:

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

Does it support auditing?

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Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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