Vitamin D3 (CAS 67-97-0): Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Vitamin D3 (CAS 67-97-0) | Vitamin D2 |
|---|---|---|
| Chemical Name | Cholecalciferol | Ergocalciferol |
| Molecular Formula | C27H44O | C28H44O |
| Molecular Weight | 384.64 g/mol | 396.65 g/mol |
| Solubility | Lipid-soluble (insoluble in water) | Lipid-soluble (insoluble in water) |
| Stability | Sensitive to light, heat, and acidic conditions | Similar degradation profile |
| Bioactivity | Higher bioavailability in humans | Lower metabolic efficiency |
2. Key Applications & Functional Properties
Core Physiological Functions
- Enhances intestinal absorption of calcium (30-40% efficiency boost) and phosphorus
- Regulates parathyroid hormone secretion for bone mineralization
- Supports immune modulation through VDR (Vitamin D Receptor) activation
Industrial Applications
- Pharmaceuticals: Treatment of rickets, osteoporosis (60,000-300,000 IU dosage forms)
- Nutraceuticals: Dietary supplements (1,000-5,000 IU daily value)
- Animal Feed: Poultry/poultry feed additive for calcium metabolism (2,000-4,000 IU/kg)
- Cosmeceuticals: Psoriasis creams (calcipotriol derivatives)
3. Industrial Use Cases
Case 1: Pharmaceutical Formulation
Challenge: Pediatric rickets prevention in low-sunlight regions
Solution: 400 IU/mL oral drops achieving 90% serum 25(OH)D normalization within 8 weeks
Case 2: Feed Additive Optimization
Challenge: Layer hen eggshell fragility
Solution: 3,000 IU/kg feed additive reduced broken eggs by 42% over 6 months
4. Client Success Stories
European Pharma Leader (Confidential)
- Integrated 200,000 IU/mL injectable solution for renal osteodystrophy
- Achieved 98% batch consistency across 12-month production
North American Nutraceutical Manufacturer
- Developed thermally stable 10,000 IU softgel (130°C/90min tolerance)
- 36-month shelf life certification under ICH Q1A guidelines
5. Contact for Technical Consultation
Request formulation guidance or quality specifications:
Email: info@vivalr.com
Tel: (86) 15866781826



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