methoxypolyethylene glycols cas 9004-74-4

Table of Contents

• Product Overview & Specifications
• Key Applications & Use Cases
• Industry Case Studies (2024)
• Procurement Guidance
• Contact for Technical Consultation

Methoxypolyethylene Glycols (mPEG, CAS 9004-74-4): Product Specifications

Technical Parameters

Quality Certifications

USP/NF Grade | REACH Registered | ISO 9001:2015 Certified Manufacturing

Critical Applications in Pharmaceutical & Industrial Sectors

1. Drug Delivery Systems

mPEG derivatives enable:

• PEGylation of proteins/peptides (extend circulation half-life)
• Lipid nanoparticle (LNP) formulations for mRNA vaccines
• Solubility enhancement for poorly water-soluble APIs

2. Biomedical Research

• Surface modification of medical devices
• Hydrogel matrices for 3D cell culture
• Controlled drug release microparticles

Verified Customer Implementations (2023-2024)

Case Study 1: mRNA Vaccine Excipient Development

Client: European Biopharma Company

Challenge: Required GMP-grade mPEG 2000 for stabilizing lipid nanoparticles in COVID-19 booster vaccines

Solution: Supplied 98.7% pure mPEG with full ICH Q3D elemental impurity documentation

Outcome: Achieved 12-month stability at 2-8°C storage

Case Study 2: Ophthalmic Drug Formulation

Client: US Ophthalmic Solutions Manufacturer

Challenge: Needed low-viscosity mPEG 350 for sustained-release eye drops

Solution: Customized narrow MW distribution (PDI <1.05)

Outcome: Extended corneal residence time by 3.2x vs standard PEG

Procurement Best Practices

Supplier Evaluation Criteria

Request Customized Technical Support

Contact our polymer science team:

Email: info@vivalr.com
Tel: (86) 15866781826