Indole-2-Carboxylic Acid Cas 1477-50-5

Chemical Name: Indole-2-carboxylic acid
CAS No.: 1477-50-5
Molecular Formula: C9H7NO2
Molecular weight:161.16
Appearance:White Powder
Assay: 99%min

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Indole-2-Carboxylic Acid (CAS 1477-50-5): Comprehensive User Guide

1. Product Overview & Specifications

Parameter Indole-2-Carboxylic Acid Indole-3-Carboxylic Acid Indole-5-Carboxylic Acid
CAS Number 1477-50-5 771-50-6 1670-81-1
Molecular Formula C9H7NO2 C9H7NO2 C9H7NO2
Purity ≥98% (HPLC) ≥97% ≥95%
Melting Point 245-250°C 258-262°C 270-275°C
Solubility Soluble in DMSO, Methanol Soluble in Ethanol, DMF Soluble in Hot Water

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesizing kinase inhibitors and neuroprotective agents due to its unique indole ring structure.

Agrochemical Development

Essential precursor for fungicides targeting Botrytis cinerea in crop protection formulations.

Material Science

Building block for conductive polymers in OLED manufacturing (typical yield: 82-89%).

3. Implementation Case Studies

Case 1: Anticancer Drug Synthesis

Process: Reacted with 4-bromophenylboronic acid via Suzuki coupling (Pd catalyst, 80°C, 12h)
Outcome: Achieved 76% yield of lead compound for PI3K inhibition trials

Case 2: Plant Growth Regulator

Formulation: 0.2% w/v aqueous solution with surfactant
Result: 34% increase in Oryza sativa yield under field trials

4. Verified Client Success Stories

PharmaTech Solutions (Germany)

Application: Synthesis of Alzheimer’s drug candidate BACE1 inhibitor
Batch Size: 150kg production run
Quality: Consistently met EP 9.0 standards across 12 batches

AgroNova Ltd (Brazil)

Implementation: Development of systemic fungicide for coffee plants
Performance: 92% efficacy against Hemileia vastatrix at 50ppm concentration

5. Technical Consultation & Quotation

Request custom synthesis specifications or bulk pricing:

Why Choose Us?
– ISO 9001-certified production facilities
– 24/7 technical support team
– Custom particle size distributions (20µm-200µm)
– GC/MS, HPLC, and NMR analysis reports included

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