Indole-2-Carboxylic Acid (CAS 1477-50-5): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Indole-2-Carboxylic Acid | Indole-3-Carboxylic Acid | Indole-5-Carboxylic Acid |
|---|---|---|---|
| CAS Number | 1477-50-5 | 771-50-6 | 1670-81-1 |
| Molecular Formula | C9H7NO2 | C9H7NO2 | C9H7NO2 |
| Purity | ≥98% (HPLC) | ≥97% | ≥95% |
| Melting Point | 245-250°C | 258-262°C | 270-275°C |
| Solubility | Soluble in DMSO, Methanol | Soluble in Ethanol, DMF | Soluble in Hot Water |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors and neuroprotective agents due to its unique indole ring structure.
Agrochemical Development
Essential precursor for fungicides targeting Botrytis cinerea in crop protection formulations.
Material Science
Building block for conductive polymers in OLED manufacturing (typical yield: 82-89%).
3. Implementation Case Studies
Case 1: Anticancer Drug Synthesis
Process: Reacted with 4-bromophenylboronic acid via Suzuki coupling (Pd catalyst, 80°C, 12h)
Outcome: Achieved 76% yield of lead compound for PI3K inhibition trials
Case 2: Plant Growth Regulator
Formulation: 0.2% w/v aqueous solution with surfactant
Result: 34% increase in Oryza sativa yield under field trials
4. Verified Client Success Stories
PharmaTech Solutions (Germany)
Application: Synthesis of Alzheimer’s drug candidate BACE1 inhibitor
Batch Size: 150kg production run
Quality: Consistently met EP 9.0 standards across 12 batches
AgroNova Ltd (Brazil)
Implementation: Development of systemic fungicide for coffee plants
Performance: 92% efficacy against Hemileia vastatrix at 50ppm concentration
5. Technical Consultation & Quotation
Request custom synthesis specifications or bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Why Choose Us?
– ISO 9001-certified production facilities
– 24/7 technical support team
– Custom particle size distributions (20µm-200µm)
– GC/MS, HPLC, and NMR analysis reports included



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