Glycyrrhetinic Acid (CAS 471-53-4): Technical Guide & Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification | Comparative Analysis |
|---|---|---|
| CAS Number | 471-53-4 | Unique identifier across suppliers |
| Molecular Formula | C30H46O4 | Consistent with pharmacopeial standards |
| Molecular Weight | 470.68–470.69 g/mol | ±0.01 g/mol variation among suppliers |
| Purity | HPLC ≥98% | Higher grades (≥99%) available upon request |
| Melting Point | 281–295°C | Varies by isomer (18α/18β configuration) |
| Solubility | Ethanol, acetic acid | Water-insoluble; requires solubilizers |
2. Key Applications
Pharmaceutical Uses
- Anti-inflammatory: Inhibits 11β-hydroxysteroid dehydrogenase for corticosteroid regulation
- Dermatology: Reduces UV-induced skin damage in SPF 30+ formulations
- Gastrointestinal: Accelerates ulcer healing (20–40 mg/day dosage)
Cosmeceutical Uses
- 0.5–2% concentration in anti-acne serums
- Stability: pH 5.0–7.0; avoid strong oxidizers
3. Usage Scenarios
Formulation Example: Anti-Aging Cream
| Component | Percentage | Function |
|---|---|---|
| Glycyrrhetinic Acid | 1.5% | Collagen synthesis booster |
| Hyaluronic Acid | 2.0% | Moisture retention |
4. Client Case Studies
Case 1: Nanjing Yuanzhi Bio-Tech
- Application: HPLC-grade reference standard (≥98%)
- Outcome: Enabled batch consistency in anti-hepatitis drug R&D
Case 2: Shanghai Tongtian Biotech
- Application: Raw material for dermatological gels
- Scale: 50 kg/month procurement since 2023
5. Request Quotation
Available packaging: 10 mg to 500 kg
Lead time: 3–7 days (stocked items)
Regulatory support: COA, MSDS, DMF files
Contact: info@vivalr.com | Tel: (86) 15866781826
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