Methyl p-toluenesulfonate CAS 80-48-8

Methyl p-Toluenesulfonate (CAS 80-48-8) Technical Guide

Table of Contents

• Product Specifications & Comparative Analysis
• Industrial Applications & Functional Properties
• Operational Protocols & Reaction Mechanisms
• Sector-Specific Implementation Cases
• Client Success Profiles
• Procurement Consultation

1. Product Specifications & Comparative Analysis

2. Industrial Applications & Functional Properties

This methylating agent demonstrates exceptional reactivity in:

• Pharmaceutical intermediates synthesis
• Dye manufacturing catalysis
• Polymer modification processes
• Alkylation reactions in petrochemical refining
• Nucleophilic substitution reactions

3. Operational Protocols & Reaction Mechanisms

3.1 Methylation Process Optimization

Optimal reaction conditions require:

• Temperature range: 40-80°C
• Anhydrous environments
• Stoichiometric control (1:1.05 molar ratio)

3.2 Safety Implementation

• PPE Requirements: Neoprene gloves + face shield
• Ventilation: Fume hood operation mandatory
• Spill Management: Neutralize with sodium bicarbonate

4. Sector-Specific Implementation Cases

4.1 API Manufacturing

Used in synthesis of antihypertensive drug intermediates through N-methylation reactions with 92% yield improvement versus conventional methods.

4.2 Specialty Chemicals

Enables production of UV-stable photoinitiators for coatings industry, achieving 150% faster curing times.

5. Client Success Profiles

Case 1: European Pharma Producer

• Challenge: Low yield in antipsychotic API synthesis
• Solution: Optimized methyl transfer protocol
• Outcome: 38% production cost reduction

Case 2: Asian Polymer Manufacturer

• Challenge: Inconsistent cross-linking in adhesives
• Solution: Controlled methylation sequencing
• Outcome: Achieved 99.2% batch consistency

6. Procurement Consultation

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