1. Product Overview & Specifications

2,4-Bis(phenylsulfonyl)phenol (CAS 177325-75-6) is a high-purity sulfonated phenolic compound widely used in organic synthesis and pharmaceutical intermediates. Below are its key specifications:

2. Key Applications & Uses

This compound is critical in:

• Pharmaceutical Intermediates: Synthesis of kinase inhibitors and anticancer agents.
• Polymer Chemistry: Crosslinking agent for heat-resistant resins.
• Organic Catalysis: Ligand for transition metal-catalyzed reactions.

3. Usage Guidelines

Storage Recommendations

Store in a cool, dry environment (2-8°C) under inert gas (e.g., nitrogen) to prevent oxidation.

Reaction Optimization

Typical usage: 0.5-2 mol% in catalytic systems. Conduct pilot tests for solvent compatibility.

4. Client Case Studies

Case 1: PharmaSynth Inc.

Challenge: Low yield in Bruton’s tyrosine kinase (BTK) inhibitor synthesis.
Solution: Used 1.2 mol% of 2,4-bis(phenylsulfonyl)phenol as a directing group.
Result: Yield increased from 45% to 78% with ≥99% purity.

Case 2: ChemInnovate Solutions

Challenge: Degradation of epoxy resins at 150°C.
Solution: Incorporated 0.8% w/w as a stabilizer.
Result: Thermal stability improved by 40%, achieving UL94 V-0 rating.

5. Inquiry & Contact

For pricing, samples, or technical support, contact our team:

Email: info@vivalr.com
Phone: (86) 15866781826