Ethyl 3-Hydroxybenzoate (CAS 7781-98-8) Comprehensive Guide
Table of Contents
- Product Overview & Specifications
- Applications & Industrial Uses
- Operational Guidelines
- Case Studies
- Client Success Stories
- Inquiry & Procurement
1. Product Overview & Specifications
| Parameter | Ethyl 3-Hydroxybenzoate | Comparative Analysis |
|---|---|---|
| CAS Number | 7781-98-8 | Unique identifier for global standardization |
| Molecular Formula | C9H10O3 | Simpler structure than higher esters (e.g., propyl derivatives) |
| Molecular Weight | 166.17 g/mol | Lower molecular weight improves solubility vs. butyl variants |
| Melting Point | 71-73°C | Higher thermal stability than para-isomers |
| Boiling Point | 187-188°C at 31 mmHg | Optimal for purification via distillation |
| Density | 1.068 g/cm³ | Standard for aromatic esters |
| Solubility | Slightly soluble in water Fully soluble in ethanol |
Superior organic solvent compatibility vs. carboxylate salts |
2. Applications & Industrial Uses
Pharmaceutical Intermediate: Key precursor in synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and antimicrobial agents.
Specialty Chemicals: Used in production of liquid crystal materials and UV stabilizers for polymers.
Research Applications:
- Mitsunobu reaction substrate for ether synthesis
- Building block for dendritic molecule construction
3. Operational Guidelines
Storage: Maintain in sealed containers under nitrogen atmosphere at ambient temperature (15-25°C)
Handling: Use PPE including nitrile gloves and chemical goggles. Ensure adequate ventilation in processing areas.
Purification: Recrystallization from ethanol/water (3:1 v/v) yields >99% purity crystals.
4. Case Studies
Case 1: Synthesis of Ethyl 3-(2-Methylbutoxy)benzoate
Reaction yield improved from 78% to 87% using optimized Mitsunobu conditions (DIAD, PPh3, THF, 0°C→RT)
Case 2: Production Scale-up for Antipyretic Drug Intermediate
Achieved batch consistency of 99.2±0.3% purity across 10-ton production runs
5. Client Success Stories
PharmaTech Solutions (Hamburg):
Reduced intermediate production costs by 22% through our customized ethyl 3-hydroxybenzoate supply program
Advanced Materials Co., Ltd. (Tokyo):
Enabled development of heat-resistant polycarbonates with 15% improved thermal stability
6. Inquiry & Procurement
Contact our technical team for:
- Custom synthesis services
- Bulk pricing (25kg+ quantities)
- Regulatory documentation support
Email: info@vivalr.com
Phone: (86) 15866781826
| Package Size | Purity | Lead Time |
|---|---|---|
| 1kg | ≥98% | 3 working days |
| 25kg | ≥99% | 5 working days |



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