Cyclopirox Olamine (CAS 41621-49-2) User Guide & Industry Insights
Table of Contents
1. Technical Specifications & Comparative Analysis
| Parameter | Cyclopirox Olamine | Ketoconazole | Terbinafine |
|---|---|---|---|
| CAS Number | 41621-49-2 | 65277-42-1 | 78628-80-5 |
| Molecular Formula | C12H17NO2·C2H7NO | C26H28Cl2N4O4 | C21H25N |
| Antifungal Spectrum | Broad-spectrum (Dermatophytes/Yeasts/Molds) | Primarily Yeasts | Dermatophytes Specific |
| Solubility (Water) | 0.1 mg/mL | 0.01 mg/mL | 0.05 mg/mL |
| pH Stability | 4.0-8.0 | 3.0-7.5 | 5.0-9.0 |
2. Multidisciplinary Applications
Pharmaceutical Formulations
- Topical Antifungal Creams (1% concentration)
- Onychomycosis Nail Lacquers (8% solution)
- Vaginal Antimycotic Suppositories
Cosmeceutical Uses
- Anti-Dandruff Shampoo Additive
- Foot Care Product Preservative
- Nail Care System Component
3. Implementation Protocols
Pharmaceutical Manufacturing
- Precision weighing (±0.1% tolerance)
- Ethanol-based dissolution (40-60°C)
- pH adjustment to 5.5-6.5
- Emulsion stabilization testing
Cosmetic Integration
- Cold process incorporation
- Compatibility testing with surfactants
- Accelerated stability trials
4. Industrial Use Cases
Case A: Antifungal Nail Solution
- Formulation: 8% Cyclopirox in hydroxypropyl chitosan matrix
- Result: 92% mycological cure rate at 48 weeks
Case B: Scalp Treatment Shampoo
- 1.5% Cyclopirox + 1% Zinc Pyrithione
- 73% reduction in Malassezia colonies
5. Verified Client Success Stories
European Dermatological Solutions Ltd.
- Application: Onychomycosis treatment system
- Outcome: Achieved EN ISO 13485 certification
- Volume: 850 kg/year procurement
AsiaCare Cosmeceuticals
- Application: Anti-fungal foot cream
- Result: 40% market share gain in Q3 2024
- Technical Support: Custom solubility enhancement
6. Procurement Consultation
For technical specifications, batch samples, or formulation support:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request current:
- GMP Compliance Certificates
- Stability Study Data Packages
- Custom Synthesis Options
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