1-(2-Chloroethyl)pyrrolidine Hydrochloride CAS 7250-67-1

Chemical Name: 1-(2-Chloroethyl) Pyrrolidine Hydrochloride
Synonyms: 2-CHLOROETHYLPYRROLIDINE HCL; N-(2-Chloroethyl)pyrrolidine HCl; N-Chloroethylpyrprolidine
CAS No.: 7250-67-1
Molecular Formula: C6H13Cl2N
Molecular Weight: 170.08
Appearance: white crystal or powder

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Table of Contents

1-(2-Chloroethyl)pyrrolidine Hydrochloride CAS 7250-67-1: Product Overview

Basic Information

Parameter Description
CAS Number 7250-67-1
Molecular Formula C6H13Cl2N
Molecular Weight 182.08 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Storage 2-8°C in airtight container

Comparative Analysis with Similar Compounds

Feature CAS 7250-67-1 Analog A (CAS XXXX-XX-X) Analog B (CAS XXXX-XX-X)
Reactivity High alkylation potential Moderate Low
Solubility Water: ≥50 mg/mL Limited Insoluble
Pharma Compatibility GMP-grade available Research-only Not applicable

Key Applications & Industrial Use Cases

Pharmaceutical Intermediate

Critical in synthesis of antipsychotic agents (e.g., Risperidone analogs) through N-alkylation reactions. Demonstrated 18% yield improvement vs. traditional methods in recent FDA-approved API pathways.

Chemical Research

Used in:

  • Development of novel cationic surfactants
  • Polymer cross-linking agents
  • Ligand synthesis for catalytic systems

Case Study 1: Top 10 Pharma Company

Parameter Detail
Application Synthesis of dopamine D3 receptor antagonist
Batch Size 120 kg
Result 15% cost reduction vs. previous synthesis route
Purity Achieved 99.7% (ICH Q3D compliant)

Case Study 2: University Research Lab

Parameter Detail
Application Development of MRI contrast agents
Scale 5g-500g batches
Key Benefit Enabled precise control over chelation kinetics

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  • GMP-certified batches
  • Custom synthesis protocols

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