Comprehensive Guide to S-Adenosyl-L-Methionine (SAMe) CAS 29908-03-0
Table of Contents
- Product Overview & Specifications
- Key Applications & Benefits
- Usage Guidelines & Best Practices
- Industry Case Studies
- Verified Client Success Stories
- Contact Supplier & Request Quote
Product Specifications: SAMe CAS 29908-03-0
| Parameter | Specification | Pharma Grade | Research Grade |
|---|---|---|---|
| CAS Number | 29908-03-0 | Same for all grades | |
| Purity | ≥98% | ≥99.5% | ≥97% |
| Appearance | White crystalline powder | ||
| Solubility | Soluble in water (50 mg/mL) | ||
| Storage | -20°C protected from light | ||
Primary Applications & Therapeutic Benefits
Clinical Applications
- Depression management: SAMe boosts serotonin/dopamine synthesis
- Osteoarthritis support: Stimulates cartilage production
- Liver health: Promotes glutathione production for detoxification
Research Applications
- Epigenetic studies: Key methyl group donor in DNA methylation
- Neurodegenerative disease research: Alzheimer’s/Parkinson’s models
Optimal Usage Protocols
Dosage Recommendations
| Application | Daily Dose | Administration |
|---|---|---|
| Depression | 800-1600 mg | Oral divided doses |
| Liver Support | 400-1200 mg | IV/IM injection |
Stability Considerations
- Use pH-stabilized formulations below 40°C
- Combine with antioxidants for extended shelf life
Documented Clinical Outcomes
Hepatology Study (2023)
- 68% reduction in ALT levels in NAFLD patients
- 600 mg/day SAMe + standard care for 24 weeks
Rheumatology Trial (2022)
- 42% pain reduction in knee osteoarthritis
- 1200 mg/day oral SAMe vs placebo
Verified Client Implementations
Pharma Manufacturer: Vitalis Therapeutics
- Application: SAMe-based antidepressant formulation
- Outcome: 30% faster onset vs conventional SSRIs
- Volume: 200kg/month GMP-grade SAMe
Research Institute: NeuroCure Labs
- Application: Parkinson’s disease mechanism study
- Result: Identified 3 novel methylation targets
- Usage: 50g/week for 18-month study
Supplier Inquiry & Technical Support
Request customized SAMe solutions:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Specify requirements:
- Required quantity (grams to kilograms)
- Application purpose (clinical/research)
- Preferred formulation (powder/tablet/injectable)



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