2-Picolinic Acid (CAS 98-98-6): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: 2-Picolinic Acid
CAS No.: 98-98-6
Molecular Formula: C6H5NO2
Molecular Weight: 123.11 g/mol
Appearance: White to pale yellow crystalline powder
Purity: ≥99%
Melting Point: 132–134°C
Solubility: Soluble in hot water and ethanol
Specification Comparison
| Parameter | Standard Grade | Pharma Grade |
|---|---|---|
| Purity | ≥99% | ≥99.5% |
| Residue on Ignition | ≤0.5% | ≤0.1% |
| Moisture Content | ≤0.5% | ≤0.2% |
2. Key Applications
- Pharmaceutical Intermediates: Used in synthesizing antiviral agents and metabolic regulators.
- Biochemical Research: Inhibits adenovirus replication in ophthalmic applications (e.g., 1.5% PCL formulation).
- Agrochemicals: Serves as a precursor for herbicide development.
- Dye Manufacturing: Key component in specialty dye synthesis.
- Electrochemical Synthesis: Utilized in electrode modification for analytical chemistry.
3. Usage Scenarios
Scenario 1: Antiviral Drug Development
In ophthalmic research, 2-Picolinic Acid (1.5% concentration) demonstrated efficacy in reducing adenovirus shedding duration by 40% in rabbit models, with no observed ocular toxicity.
Scenario 2: Electrochemical Analysis
Poly-2-picolinic acid modified electrodes enable precise dopamine detection at 0.1–50 μM levels via voltammetry, achieving 95% recovery rates in clinical samples.
4. Client Case Studies
Case Study 1: Shandong Haizhou Bioengineering
Application: Bulk production of herbicide intermediates
Outcome: Achieved 99.2% purity at 20 MT/month capacity
Packaging: 25 kg fiber drums with moisture-proof lining
Case Study 2: Beijing Odyssey Chemical
Application: Antiviral drug R&D
Outcome: Developed topical formulation reducing viral load by 60% in preclinical trials
Storage: Controlled environment (15–25°C, RH <40%)
Case Study 3: Leyan Reagent
Application: Research-grade chemical supply
Inventory: Maintains 700+ kg stock with same-day shipping
Quality: Meets USP-NF standards for analytical applications
5. Contact for Technical & Commercial Inquiries
Email: info@vivalr.com
Tel: (86) 15866781826
Available: Mon–Fri, 8:30 AM – 5:30 PM (GMT+8)
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