Ethyl Diphenylphosphinite CAS 719-80-2: Technical Guide & Application Insights
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications in Organic Synthesis
- 3. Industry Case Studies
- 4. Real Client Success Stories
- 5. Request Customized Solutions
1. Product Overview & Specifications
| Parameter | Ethyl Diphenylphosphinite | Similar Phosphinite Derivatives |
|---|---|---|
| CAS Number | 719-80-2 | Varies by derivative |
| Molecular Formula | C14H15OP | Depends on substituents |
| Molecular Weight | 230.24 g/mol | 200-260 g/mol range |
| Appearance | Colorless to pale yellow liquid | Liquid or crystalline forms |
| Purity (GC) | >98% | Typically 95-99% |
| Storage Conditions | 2-8°C under inert gas | Similar requirements |
2. Key Applications in Organic Synthesis
Core Functional Uses:
- Ligand in transition metal-catalyzed cross-coupling reactions
- Key intermediate for Staudinger-type reactions
- Nucleophilic catalyst in asymmetric synthesis
- Precursor for phosphorus-containing heterocycles
3. Industry Case Studies
Pharmaceutical Intermediate Synthesis:
Used in Buchwald-Hartwig amination for anticancer drug candidates, achieving 92% yield improvement over traditional methods.
Advanced Material Development:
Enabled creation of flame-retardant polymers with 40% reduced phosphorus loading compared to standard additives.
4. Real Client Success Stories
Case 1: Top 10 Pharma Company (Confidential)
– Challenge: Low yield (≤55%) in API intermediate synthesis
– Solution: Implemented our phosphinite as ligand in Pd-catalyzed step
– Result: Yield increased to 88% with 99.5% purity
Case 2: University Research Team
– Application: Development of chiral catalysts for asymmetric hydrogenation
– Outcome: Achieved 95% ee in test reactions, published in JACS
5. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (1kg to ton quantities)
- Custom purity specifications (Up to 99.9%)
- Technical support for reaction optimization
Email: info@vivalr.com
Phone: (86) 15866781826



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