4-Dodecanolide (CAS 2305-05-7): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Dodecanolide (CAS 2305-05-7) is a high-purity cyclic ester widely used in flavors, fragrances, and pharmaceutical intermediates. Key specifications include:
| Parameter | Value |
|---|---|
| CAS Number | 2305-05-7 |
| Molecular Formula | C12H22O2 |
| Purity | ≥99% (GC) |
| Melting Point | 32-34°C |
| Boiling Point | 280°C at 760 mmHg |
2. Applications & Use Cases
Key Industries Served:
- Flavor & Fragrance: Milky/creamy note enhancer in food additives and perfumes.
- Pharmaceuticals: Intermediate for macrolide antibiotics synthesis.
- Cosmetics: Fixative in luxury skincare products.
Operational Workflow Example:
In dairy flavor production, 0.01-0.05% 4-Dodecanolide is added during the emulsification phase to enhance creaminess without altering pH stability.
3. Industry Case Studies
Case Study 1: FlavorHouse International
Challenge: Needed stable creamy note for plant-based dairy alternatives.
Solution: 4-Dodecanolide at 0.03% concentration in base formulation.
Result: 22% improvement in sensory panel scores vs. γ-Dodecalactone.
Case Study 2: VitaPharm Co.
Challenge: Required high-purity lactone for antibiotic R&D.
Solution: Custom purification to 99.7% GC purity.
Result: Reduced catalytic reaction time by 40%.
4. Technical Comparison
| Parameter | 4-Dodecanolide | γ-Dodecalactone |
|---|---|---|
| Odor Threshold | 0.8 ppb | 5.2 ppb |
| Thermal Stability | Stable to 250°C | Degrades at 200°C |
| Solubility in EtOH | Complete | 85% |
5. Request a Quote
Contact our technical team for formulation support or bulk pricing:



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