Rans-4-amino-cyclohexane Carboxylic Acid Hydrochloride Cas 27960-59-4

Chemical Name: Rans-4-amino-cyclohexane Carboxylic Acid Hydrochloride
CAS No.: 27960-59-4
Molecular Fomula: C7H14ClNO2
Molecular weight: 179.64
Appearance: White solid
Assay:≥99.0%

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Rans-4-amino-cyclohexane Carboxylic Acid Hydrochloride (CAS 27960-59-4): Comprehensive Guide

Table of Contents

Product Overview & Specifications

Parameter Details
CAS Number 27960-59-4
Chemical Name Rans-4-aminocyclohexanecarboxylic acid hydrochloride
Molecular Formula C7H14ClNO2
Molecular Weight 191.65 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Solubility Soluble in water, DMSO, methanol

Comparative Analysis

Feature Rans-4-amino-CHCA HCl Similar Derivatives
Stability Superior hygroscopic resistance Moderate moisture sensitivity
Bioavailability Enhanced membrane permeability Variable absorption rates
Synthesis Yield 85-90% optimized process 70-80% typical yield

Key Applications

Pharmaceutical Intermediates

Critical component in cephalosporin antibiotics synthesis, particularly for Gram-negative bacteria treatments.

Biochemical Research

Used as:

  • Protease inhibition studies
  • Peptide conformation analysis
  • Cell permeability enhancer in drug delivery systems

Industrial Applications

Essential for:

  • High-performance polymer crosslinking
  • Metal-organic framework (MOF) synthesis

Usage Scenarios

Antibiotic Synthesis Protocol

  1. Dissolve 5g compound in 100ml deionized water
  2. Maintain reaction at pH 6.8-7.2
  3. React with β-lactam intermediate at 45°C for 6hrs

Research-grade Preparation

For cell studies:

  • Prepare 10mM stock solution in PBS
  • Use at 50-200μM concentration range

Client Case Studies

Case 1: PharmaTech Solutions

  • Application: Third-generation cephalosporin development
  • Result: 40% improved bacterial clearance rate vs previous analogs
  • Volume: 150kg annual procurement

Case 2: University of BioResearch

  • Usage: Transmembrane transport mechanism studies
  • Outcome: Published in Nature Chemical Biology (2023)
  • Purity Requirement: ≥99% for NMR characterization

Case 3: Materials Innovators Inc.

  • Implementation: Conductive polymer synthesis
  • Achievement: 25% conductivity enhancement
  • Batch Consistency: 98.2-99.1% purity across 10 batches

Contact for Quotation & Technical Support

Request custom synthesis, bulk pricing, or COA:

Technical consultation available for:

  • Custom purity specifications (90-99.9%)
  • GMP-grade manufacturing options
  • Stability profile data
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