potassium methoxide cas 865-33-8

Assay: 30%-32%
Appearance: Clear liquid
Capacity: 5000MT per year
Packaging: 1000kg IBC drum,ISO Tank
Sample: available

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Potassium Methoxide (CAS 865-33-8): Comprehensive User Guide

1. Product Overview & Specifications

Potassium Methoxide (CAS 865-33-8) is a highly reactive alkaline compound widely used in organic synthesis, biodiesel production, and pharmaceutical manufacturing. Its chemical formula is CH3OK, with a molecular weight of 70.13 g/mol.

Key Specifications:

Parameter Value
CAS Number 865-33-8
Purity 95%-99% (industrial grade)
Appearance White to yellowish powder or solution
Storage Temperature 2-8°C (dry, inert atmosphere)

2. Key Applications & Use Cases

2.1 Biodiesel Catalysis

As a transesterification catalyst, potassium methoxide accelerates the conversion of triglycerides to fatty acid methyl esters (FAMEs), achieving >98% yield under optimized conditions.

2.2 Pharmaceutical Synthesis

Used in nucleophilic substitution reactions for APIs like antihypertensive drugs. Enables precise control of reaction kinetics at 40-60°C.

2.3 Polymer Production

Facilitates anionic polymerization of ethylene oxide, producing PEGs with controlled molecular weights (1,000-20,000 Da).

3. Industrial Case Studies

Case 1: BioFuel Corp (Germany)

Challenge: Achieve 99.5% biodiesel purity with <30 ppm soap formation.
Solution: 0.5 wt% potassium methoxide in methanol at 65°C.
Result: 99.7% FAME yield, 22 ppm soaps, 15% reduced catalyst cost.

Case 2: MediPharma Ltd (USA)

Challenge: Optimize β-blocker synthesis with <0.1% side products.
Solution: 2.2 molar equivalents in THF at -20°C.
Result: 92% selectivity, 0.05% impurities, 20% faster reaction.

4. Technical Parameters Comparison

Parameter KOMe NaOMe LiOMe
Basicity (pKa) 17.5 15.5 13.5
Solubility in MeOH (g/100ml) 32 45 28
Typical Reaction Temp 50-70°C 60-80°C 30-50°C

5. Inquiry & Contact

Request technical datasheets or samples:

Global shipping available. MSDS and COA provided upon request.

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