5-Cyanoindole (CAS 15861-24-2) User Guide: Applications, Case Studies & Procurement Insights
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Industrial Uses
- 3. Operational Guidelines & Best Practices
- 4. Real-World Case Studies
- 5. Strategic Procurement Recommendations
- 6. Contact for Custom Solutions
1. Product Specifications & Comparative Analysis
| Parameter | 5-Cyanoindole | 5-Fluoroindole | 5-Bromoindole |
|---|---|---|---|
| CAS Number | 15861-24-2 | 399-51-9 | 10075-50-0 |
| Molecular Formula | C9H6N2 | C8H6FN | C8H6BrN |
| Purity Grade | ≥98% (HPLC) | ≥97% | ≥95% |
| Key Advantage | Superior electrophilicity | Enhanced bioavailability | Halogen bond donor capacity |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
5-Cyanoindole serves as critical building block for:
- Kinase inhibitor development (e.g., VEGF-R2 inhibitors)
- Antiviral compound synthesis targeting RNA viruses
- Oncology drug candidates with apoptosis-inducing properties
Advanced Material Science
- Electron-deficient component in OLED emitters
- Coordination sites for metal-organic frameworks (MOFs)
- Conductive polymer precursors for flexible electronics
3. Operational Guidelines & Best Practices
Handling Protocols
- Storage: Maintain under inert gas (N2/Ar) at 2-8°C
- Solubility: 23 mg/mL in DMSO; 15 mg/mL in DMF
- Incompatibilities: Strong oxidizers, concentrated acids
4. Real-World Case Studies
Case 1: Oncology Drug Development
Client: PharmaTech Inc. (USA)
Application: Synthesized novel PI3Kδ inhibitor using 5-cyanoindole as core scaffold
Outcome: Achieved 82% tumor growth inhibition in xenograft models
Case 2: OLED Material Innovation
Client: Material Innovations Co. (Germany)
Application: Developed deep-blue emitter with CIEy ≤0.08 at 5% doping ratio
Performance: EQE increased from 8.2% to 12.7% vs. standard materials
5. Strategic Procurement Recommendations
- Validate supplier ISO 9001:2015 certification
- Request batch-specific 13C NMR spectra
- Confirm stability data beyond standard 24-month claim
6. Contact for Custom Solutions
For technical specifications or bulk quotations:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Our experts provide:
- Custom purity grades (up to 99.9%)
- Gram-to-kilogram scale production
- Regulatory support for FDA/EMA filings



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