minoxidil cas 38304-91-5

Chemical Name:Minoxidil
CAS No.:38304-91-5
Molecular Formula: C9H15N5O
Molecular Weight: 209.25
Appearance:White powder

related documents:

COA of Minoxidil CAS 38304-91-5
TDS of Minoxidil CAS 38304-91-5

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Minoxidil (CAS 38304-91-5) Comprehensive User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Pharmaceutical Grade Industrial Grade
CAS Number 38304-91-5
Molecular Formula C9H15N5O
Purity ≥99% (CP/EP/USP) 97-99%
Appearance White crystalline powder Off-white powder
Melting Point 272-274°C 268-272°C

2. Key Applications & Pharmacological Mechanisms

Therapeutic Applications:

  • Androgenetic alopecia treatment (topical solutions 2-5%)
  • Hypertension management (oral administration)
  • Vasodilation in refractory cardiovascular conditions

Mechanism of Action:
Potassium channel activation induces arteriolar vasodilation, reducing peripheral resistance. In dermatological applications, prolongs anagen phase via stimulation of hair follicle progenitor cells.

3. Operational Protocols & Best Practices

Pharmaceutical Formulation:

  1. Solution Preparation: Dissolve in propylene glycol (2-5% w/v)
  2. Stability Control: Maintain pH 6.0-7.5
  3. Preservation: Use ethanol (30-50% v/v) as stabilizer

4. Industry Implementation Case Studies

Case 1: Topical Solution Production
A European pharma company achieved 18-month stability using our GMP-grade material in ethanol-propylene glycol vehicles, meeting ICH Q1A guidelines.

Case 2: Transdermal Patch Development
Asian manufacturer enhanced bioavailability by 40% through optimized matrix systems using our high-purity Minoxidil.

5. Client Success Stories

Client A: Global Dermatology Leader
“Sourced 98.5% pure Minoxidil for 3 years with consistent HPLC profiles and <0.3% impurity levels, supporting FDA submissions."

Client B: Cardiovascular Research Institute
“Received customized particle size distributions (10-50μm) for inhalation studies, accelerating pulmonary delivery research.”

6. Procurement Consultation

For technical specifications sheets or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Request quotation parameters:

  • Required quantity (grams to metric tons)
  • Certification needs (GMP/CEP/USP)
  • Custom particle size requirements
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