3-chlorotoluene cas 108-41-8

Chemical Name: 3-Chlorotoluene
CAS No.: 108-41-8
Molecular Formula: C7H7Cl
Molecular Weight: 126.58
Appearance: Clear and colorless liquid

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3-Chlorotoluene (CAS 108-41-8) User Guide

Contents

1. Product Overview & Specifications

Parameter Value
CAS Number 108-41-8
IUPAC Name 1-Chloro-3-methylbenzene
Molecular Formula C7H7Cl
Molecular Weight 126.58 g/mol
Appearance Colorless liquid
Purity >99% (GC)
Boiling Point 162°C
Density 1.07 g/cm³

2. Key Applications

2.1 Pharmaceutical Intermediates

Widely used in synthesizing non-steroidal anti-inflammatory drugs (NSAIDs) and antihistamines.

2.2 Agrochemical Production

Key component in fungicide and herbicide formulations such as chlorothalonil precursors.

3. Technical Comparison with Isomers

Property o-Chlorotoluene m-Chlorotoluene p-Chlorotoluene
CAS Number 95-49-8 108-41-8 106-43-4
Boiling Point 159°C 162°C 162°C
Reactivity High electrophilicity Moderate reactivity Low steric hindrance

4. Usage Guidelines

4.1 Storage Recommendations

Store in airtight containers at 15-25°C with inert gas blanket.

4.2 Safety Protocols

Required PPE: Chemical goggles, neoprene gloves, A1B1E1K1-rated respirator.

5. Case Studies

5.1 Pharmaceutical Intermediate Synthesis

ABC Pharma achieved 92% yield in NSAID production using optimized Ullmann coupling conditions (120°C, CuI catalyst).

5.2 Dye Manufacturing Process

DEF Chemicals reduced reaction time by 40% through microwave-assisted Friedel-Crafts alkylation.

6. Client Success Stories

6.1 AgroChem India Ltd.

Application: Chlorothalonil precursor synthesis
Results: 15% cost reduction vs. traditional routes
Feedback: “Consistent >99.5% purity enabled GMP compliance”

6.2 EuroPharma GmbH

Application: Antihistamine API production
Scale: 8 MT/month
Technical Support: Received custom particle size optimization

7. Request Quotation

Contact our chemical experts for bulk pricing and custom synthesis solutions:
Email: info@vivalr.com
Tel: (86) 15866781826

Why choose us:
– ISO 9001-certified production
– 24/7 technical support
– Global logistics network

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