1-Hexadecylpyridinium Bromide (Cetrimonium Bromide) User Guide
Table of Contents
1. Product Overview & Specifications
1-Hexadecylpyridinium bromide (CAS 140-72-7), commonly known as Cetrimonium Bromide (CTAB), is a quaternary ammonium compound with the molecular formula C21H38BrN. This cationic surfactant is widely recognized for its antimicrobial and phase-transfer catalytic properties.
| Parameter | Specification | CTAB vs SDS |
|---|---|---|
| Appearance | White crystalline powder | More stable than SDS |
| Purity | ≥99% | Higher catalytic efficiency |
| Solubility | Water/ethanol soluble | Better thermal stability |
| CMC (25°C) | 0.92 mM | Lower than SDS |
2. Key Applications & Use Cases
Core Applications:
- Pharmaceuticals: Antimicrobial agent in topical formulations
- Cosmetics: Hair conditioner component in shampoos
- Molecular Biology: Nucleic acid isolation buffer additive
- Nanotechnology: Template for gold nanoparticle synthesis
Technical Advantages:
| Industry | Concentration Range | Optimal pH |
|---|---|---|
| DNA Extraction | 2-4% w/v | 8.0-9.0 |
| Cosmetic Formulations | 0.5-2% | 5.5-6.5 |
3. Performance Comparison
| Property | CTAB | DTAB | TTAB |
|---|---|---|---|
| Antimicrobial Efficacy | ★★★★☆ | ★★★☆☆ | ★★☆☆☆ |
| Critical Micelle Concentration | 0.92 mM | 15 mM | 3.8 mM |
4. Industry Implementation Examples
Case Study 1: Pharmaceutical Disinfectant
Challenge: Hospital-grade surface sanitizer requiring 99.99% bacterial reduction
Solution: 0.5% CTAB formulation with ethanol synergy
Result: Achieved 5-log reduction against S. aureus in 2 minutes
Case Study 2: Cosmetic Conditioning
Challenge: Reduce hair shaft porosity in keratin treatments
Solution: 1.2% CTAB in leave-in conditioner
Result: 40% improvement in combability metrics
5. Client Success Stories
ABC Biotech (Shanghai)
Application: Plant genomic DNA extraction
Implementation: Custom 3% CTAB lysis buffer
Outcome: Increased DNA yield by 220% compared to SDS method
Global Personal Care Inc.
Application: Anti-dandruff shampoo formulation
Implementation: 0.8% CTAB + zinc pyrithione system
Outcome: 73% reduction in Malassezia colonies (ASTM E2315)
6. Consultation & Ordering
Contact our technical team for:
- Custom concentration formulations
- GMP-certified manufacturing options
- Technical documentation (SDS, COA)
Email: info@vivalr.com
Phone: (86) 15866781826
Request bulk pricing (50kg+ orders): Quote Inquiry


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