Comprehensive Guide to 4-(Trifluoromethyl)nicotinic Acid
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Use Cases
- 3. Industry Case Studies
- 4. Usage Guidelines & Safety
- 5. Request a Quote
1. Product Overview & Specifications
| Parameter | 4-(Trifluoromethyl)nicotinic Acid | Nicotinic Acid Derivatives |
|---|---|---|
| CAS Number | 131747-63-2 | Varies |
| Molecular Formula | C7H4F3NO2 | – |
| Purity | >98% | 70-99% |
| Melting Point | 178-182°C | 160-220°C |
| Solubility | DMSO, Methanol | Variable |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors for oncology drugs due to trifluoromethyl group enhancing metabolic stability.
Agrochemicals
Critical component in next-generation herbicides and fungicides with improved rainfastness.
Material Science
Building block for liquid crystal materials and OLED electron-transport layers.
3. Industry Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesized PI3K inhibitor using 4-(Trifluoromethyl)nicotinic acid as key intermediate
Result: 40% improved bioavailability vs non-fluorinated analogs
Case 2: High-Performance Fungicide
Client: EU Agrochemical Manufacturer
Application: Developed systemic fungicide with 0.5 ppm effective concentration
Result: 98% disease control in wheat field trials
4. Usage Guidelines & Safety
| Aspect | Requirement |
|---|---|
| Storage | 2-8°C in sealed container under inert gas |
| Handling | Use nitrile gloves + fume hood |
| Shelf Life | 24 months when stored properly |
5. Request a Quote
Email: info@vivalr.com
Phone: (86) 15866781826
Available Forms: Powder (1kg-100kg), Custom synthesis (100g-10kg)
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