Chemical Name: DIPSO
CAS No.: 68399-80-4
Molecular Formula: C7H17NO6S
Molecular Weight: 243.28
Appearance: White powder
Parameter | DIPSO (CAS 68399-80-4) |
---|---|
Chemical Name | 3-(Bis(2-hydroxyethyl)amino)-2-hydroxypropanesulfonic acid |
Molecular Formula | C7H17NO6S |
Molecular Weight | 243.28 g/mol |
Appearance | White crystalline powder |
Solubility | Water: 0.1M at 20°C |
pH Range | 7.0 - 8.2 (effective buffering zone) |
Melting Point | 189-192°C |
LogP | -1.40 |
PSA | 126.68 Ų |
DIPSO is a zwitterionic biological buffer with critical roles in:
Dissolve 24.3g in 1L distilled water to prepare 0.1M solution. Filter sterilize (0.22μm) for cell culture use.
Buffer | pH Range | Temperature Stability | Ionic Strength |
---|---|---|---|
DIPSO | 7.0-8.2 | ±0.02 pH/°C | Low |
HEPES | 6.8-8.2 | ±0.03 pH/°C | Moderate |
MOPS | 6.5-7.9 | ±0.01 pH/°C | Low |
A Tier 1 university laboratory successfully utilized 10mM DIPSO solution to maintain pH stability during 72-hour oocyte maturation studies, achieving 92% viability rates.
GMP facility implemented DIPSO-based buffer systems for monoclonal antibody characterization, reducing buffer-related interference in HPLC analyses by 38% compared to traditional buffers.
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