(S)-(+)-3-Hydroxytetrahydrofuran

Product Name:(S)-(+)-3-Hydroxytetrahydrofuran
CAS:86087-23-2
MFC4H8O2
MW:88.11
EINECS:425-090-2
MOL File:86087-23-2.mol

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Comprehensive Guide to (S)-(+)-3-Hydroxytetrahydrofuran

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter (S)-(+)-3-Hydroxytetrahydrofuran Similar Compounds
CAS Number 130099-92-8 Varies by isomer
Molecular Formula C₄H₈O₂ Same formula, different stereochemistry
Optical Purity >99% ee 85-99% ee (market average)
Storage Conditions 2-8°C in inert atmosphere Room temperature (racemic forms)

2. Industrial Applications & Functional Uses

Pharmaceutical Intermediate: Key chiral building block for antiviral medications (e.g., HIV protease inhibitors) and β-lactam antibiotics.

Agrochemical Synthesis: Essential component in production of stereospecific herbicides and fungicides.

Polymer Chemistry: Monomer for biodegradable polymers with controlled degradation rates.

3. Operational Protocols & Safety Measures

Handling Requirements: Use nitrogen-purged environments for oxygen-sensitive reactions

Reaction Optimization: Maintain pH 6.5-7.5 in aqueous solutions to prevent racemization

Purification Methods: Recommended chromatographic techniques for maintaining enantiomeric excess

4. Documented Client Implementations

Case Study 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company

Challenge: Required 50kg batch with >99.5% ee for clinical trial material

Solution: Custom synthesis protocol with continuous chiral purification

Outcome: Successful Phase II trials with 92% yield maintained

Case Study 2: Sustainable Polymer Production

Client: European Bioplastics Manufacturer

Challenge: Develop compostable packaging material meeting EU 2025 standards

Solution: Optimized ring-opening polymerization using our chiral substrate

Result: Achieved 40% faster degradation rate than market alternatives

5. Procurement & Technical Support

Custom Synthesis Available: Batch sizes from 100g to 500kg

Quality Assurance: Full NMR, HPLC, and chiral GC analysis reports included

Expedited Shipping: Global logistics network with temperature-controlled transport

Contact our technical team for formulation assistance:

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