Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 7-Hydroxyisoquinoline | Analog Compound (8-Hydroxyisoquinoline) |
|---|---|---|
| CAS Number | 7651-83-4 | 3482-14-2 |
| Molecular Formula | C9H7NO | C9H7NO |
| Molecular Weight | 145.16 g/mol | 145.16 g/mol |
| Melting Point | 226-228°C | 220-222°C |
| Boiling Point | 332.1±15.0°C | 328.5±14.5°C |
| Density | 1.3±0.1 g/cm³ | 1.28±0.1 g/cm³ |
Key Differentiators
- Superior thermal stability (3.6% lower decomposition rate at 250°C vs analogs)
- Enhanced solubility in polar solvents (12% higher in ethanol/water mixtures)
2. Detailed Applications
Pharmaceutical Intermediates
Primary application in synthesis of:
- Antineoplastic agents (Phase II clinical trial components)
- Neurological drug precursors (Dopamine analogs)
Organic Synthesis
- Ligand in transition metal catalysis (Cu(II)/Fe(III) complexes)
- Building block for heterocyclic compound development
Material Science
- UV-stabilizing additive in polymer matrices
- Corrosion inhibitor component (pH 3-11 stability)
3. Operational Guidelines
Storage Protocol
- Maintain inert atmosphere (N2 >99.995%)
- Temperature: 2-8°C for long-term storage
Handling Requirements
- PPE: Nitrile gloves (0.11mm minimum), splash goggles
- Ventilation: ≥4 ACH laboratory-grade fume hood
4. Industry Use Cases
Pharmaceutical Manufacturing
Used in continuous flow synthesis of:
- PARP inhibitors (Batch yield improvement: 18-22%)
- Antimalarial drug intermediates (Purity >99.8%)
Academic Research
- Key reagent in asymmetric catalysis studies (J. Org. Chem. 2024)
- Substrate for enzyme inhibition assays (IC50 2.3μM)
5. Client Success Stories
Case Study 1: Top 10 Pharma Company
- Application: Scale-up of kinase inhibitor production
- Results: 30% reduction in side products vs previous intermediates
- Throughput: 850kg/month GMP-grade material
Case Study 2: University Research Consortium
- Application: Development of novel metal-organic frameworks
- Outcome: 2 patents filed for catalytic systems
- Publication: Nature Chemistry (2024 Impact Factor: 24.8)
6. Contact for Technical Consultation
For bulk orders (>5kg) or custom synthesis requirements:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Technical support available 24/7 with average response time <45 minutes


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