2-Bromo-5-hydroxypyrazine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Bromo-5-hydroxypyrazine (CAS 1020707-70-4) is a halogenated pyrazine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99.5% (HPLC) | 98.0% | 97.5% |
| Melting Point | 142-145°C | 138-142°C | 135-140°C |
| Solubility | DMSO, Ethanol | DMSO only | Limited |
2. Key Applications
2.1 Pharmaceutical Intermediates
Critical building block for:
- Kinase inhibitor development
- Anticancer drug candidates
- Antiviral compounds
2.2 Agrochemical Synthesis
Used in creation of:
- Next-generation herbicides
- Fungicide precursors
3. Usage Guidelines
3.1 Handling Recommendations
- Store at 2-8°C under inert atmosphere
- Use anhydrous conditions for reactions
3.2 Reaction Optimization
Typical reaction conditions:
| Reaction Type | Catalyst | Yield |
|---|---|---|
| Suzuki Coupling | Pd(PPh3)4 | 82-88% |
4. Application Case Studies
4.1 Anticancer Drug Development
Challenge: Create selective PI3K inhibitors
Solution: Used as key intermediate in scaffold modification
Result: 15% improved selectivity vs. competitors
5. Client Success Stories
5.1 PharmaTech Solutions (USA)
Achieved 92% yield in scale-up production of BTK inhibitors using our GMP-grade material.
5.2 AgroChem Ltd. (Germany)
Developed novel fungicide with 40% improved efficacy using our custom synthesis services.
6. Request Custom Solutions
Contact our technical team for:
- Bulk quantities (100kg+ available)
- Custom purity requirements
- Technical documentation support
Email: info@vivalr.com
Tel: (86) 15866781826
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8. Proper chemical nomenclature and CAS registration
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