5,6,7,8-Tetrahydroquinoline: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
5,6,7,8-Tetrahydroquinoline (CAS 10500-57-9) is a hydrogenated derivative of quinoline, widely used in pharmaceuticals, agrochemicals, and specialty chemicals.
Technical Parameters
| Parameter | Specification | Quinoline Comparison |
|---|---|---|
| Chemical Name | 5,6,7,8-Tetrahydroquinoline | Quinoline (no saturation) |
| Molecular Formula | C9H11N | C9H7N |
| Purity | ≥99% (HPLC) | Typically 95-98% |
| Boiling Point | 248-250°C | 237°C |
| Solubility | Miscible with organic solvents | Limited water solubility |
| Storage | 2-8°C in inert atmosphere | Room temperature (oxidizes) |
2. Key Applications
Pharmaceutical Intermediates
- Antimalarial drug synthesis (e.g., Chloroquine analogs)
- Neurological disorder treatments
- Antibacterial agent precursors
Agrochemical Uses
- Insecticide synergists
- Herbicide stabilizers
- Fungicide carriers
3. Usage Scenarios by Industry
Pharma Production Workflow
- Reaction vessel charging under N2
- Catalytic hydrogenation at 80-100°C
- Purification via fractional distillation
Electronics Industry Application
As electron-transport layer in OLED devices, improving device lifetime by 40% vs. standard materials.
4. Client Case Studies
Case 1: European Pharma Manufacturer
| Challenge | Solution | Result |
|---|---|---|
| Low yield in antimalarial API synthesis | Switched to 99.5% pure 5,6,7,8-Tetrahydroquinoline | Yield increased from 68% to 92% |
Case 2: US Agrochemical Company
| Problem | Implementation | Outcome |
|---|---|---|
| Pesticide formulation instability | Added 2% w/w as stabilizer | Shelf life extended from 6 to 18 months |
5. Request Custom Quotes
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- GMP-grade material
- Custom synthesis protocols
Email: info@vivalr.com
Phone: (86) 15866781826
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