6-Bromonicotinic acid

Product Name:6-Bromonicotinic acid
CAS:6311-35-9
MFC6H4BrNO2
MW:202.01
EINECS:628-671-0
MOL File:6311-35-9.mol

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Table of Contents

6-Bromonicotinic Acid Overview

Technical Specifications

Parameter Value
CAS Number 6311-35-9
Molecular Formula C6H4BrNO2
Purity ≥98% (HPLC)
Melting Point 205-208°C
Storage 2-8°C in dark

Grade Comparison

Feature Industrial Grade Pharma Grade
Purity 95-97% ≥99%
Heavy Metals <50ppm <10ppm
Price Range $120-150/kg $450-600/kg

Industrial Applications

Pharmaceutical Intermediate

Critical component in synthesis of kinase inhibitors (e.g., EGFR inhibitors) with demonstrated 30% yield improvement over alternative brominated compounds.

Agrochemical Production

Key building block for next-gen fungicides requiring Br-N bond stability at high temperatures (tested up to 300°C).

Application Scenarios

Case 1: Anticancer Drug Development

Shanghai PharmTech reduced synthesis steps from 7 to 3 in PD-1/PD-L1 inhibitor development using our GMP-grade material.

Case 2: Crop Protection Formulation

AgroSolutions Inc. achieved 92% pest control efficacy in field tests using derivatives of our bromonicotinic acid.

Client Implementations

ABC Pharmaceuticals (Germany)

Annual Purchase: 850kg
Application: Continuous flow synthesis of JAK2 inhibitors
Result: Reduced production costs by 18% vs. traditional bromination methods

ChemInnovate Corp (USA)

Annual Purchase: 2.3MT
Application: High-throughput screening of antiviral compounds
Outcome: Identified 3 lead candidates in 6-month accelerated program

Request Customized Solutions

Technical Support

Our chemists provide:
– Batch-specific COA documentation
– Regulatory compliance guidance (REACH, FDA)
– Custom synthesis scale-up protocols

Contact Information

Email: info@vivalr.com
Tel: (86) 15866781826
Service Hours: Mon-Fri 8:00-17:00 GMT+8

Quote Request Form

Submit requirements for:
– Bulk pricing (100kg+ orders)
– Custom purity specifications
– Safety documentation packages

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