5-Pyrimidinylboronic Acid: Comprehensive Product Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Applications in Pharmaceutical & Material Science
- Operational Protocols & Best Practices
- Industry-Specific Use Cases
- Client Success Stories
- Procurement & Technical Support
Product Specifications & Comparative Analysis
| Parameter | 5-Pyrimidinylboronic Acid | Standard Boronic Acids |
|---|---|---|
| CAS Number | 1072940-54-6 | Varies by compound |
| Molecular Formula | C4H5BN2O2 | Dependent on structure |
| Purity Grade | ≥98% (HPLC) | Typically 95-97% |
| Storage Conditions | 2-8°C under inert gas | Room temperature |
Applications in Pharmaceutical & Material Science
Suzuki-Miyaura Cross-Coupling Reactions
Enables synthesis of biaryl compounds through Pd-catalyzed reactions with halogenated pyrimidines.
Kinase Inhibitor Development
Critical intermediate for tyrosine kinase inhibitors targeting cancer pathways (EGFR/VEGFR).
Operational Protocols & Best Practices
Reaction Optimization
Recommended conditions: 1.5 eq boronic acid, Pd(PPh3)4 (2 mol%), K2CO3 base in THF/H2O (3:1) at 80°C.
Industry-Specific Use Cases
Antiviral Drug Synthesis
Used in production of Remdesivir analogs through nucleoside modifications.
Client Success Stories
Case 1: Top 10 Pharma Company
Accelerated JAK2 inhibitor development cycle by 40% through improved coupling efficiency.
Case 2: University Research Team
Enabled synthesis of novel OLED materials with 15% higher luminous efficiency.
Procurement & Technical Support
Contact our chemistry experts for batch-specific COA or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
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