2-Chloro-4-amino-6,7-dimethoxyquinazoline

Product Name:2-Chloro-4-amino-6
7-dimethoxyquinazoline
CAS:23680-84-4
MFC10H10ClN3O2
MW:239.66
EINECS:245-821-7
MOL File:23680-84-4.mol

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2-Chloro-4-amino-6,7-dimethoxyquinazoline: Ultimate Product Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 851677-52-4 851677-53-5 851677-54-6
Purity ≥98% (HPLC) ≥95% ≥97%
Solubility DMSO: 50 mg/mL DMSO: 30 mg/mL DMSO: 45 mg/mL

2. Key Applications in Pharmaceutical Research

Primary applications include:

  • EGFR kinase inhibition studies
  • Intermediate for gefitinib analogs
  • Antiangiogenic compound development

3. Operational Guidelines & Best Practices

Recommended storage: -20°C under nitrogen atmosphere. For biological testing:

  1. Prepare 10 mM stock solution in DMSO
  2. Use within 3 months with proper aliquoting

4. Industry Case Studies

Case Study 1: Oncology Research (PharmaCorp, 2023)

Used in developing third-generation EGFR inhibitors showing 83% tumor growth inhibition in xenograft models.

Case Study 2: Academic Screening (Stanford University, 2024)

Identified as lead compound in high-throughput screening for rare sarcoma targets.

5. Strategic Procurement Considerations

Factor Evaluation Criteria
Quality Assurance Require COA with NMR/HPLC-MS documentation
Scalability Verify multi-kilogram production capacity

6. Supplier Consultation

Contact our technical team for batch-specific data:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826
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