2-Methyl-5-pyrimidinamine

Product Name:2-Methyl-5-pyrimidinamine
CAS:39889-94-6
MFC5H7N3
MW:109.13
EINECS:
MOL File:39889-94-6.mol

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2-Methyl-5-pyrimidinamine Buyer’s Guide 2025

Table of Contents

Product Specifications & Comparative Analysis

Parameter Pharma Grade Industrial Grade Research Grade
Purity ≥99.8% ≥98.5% ≥97.0%
Molecular Weight 109.13 g/mol
Appearance White crystalline Off-white powder Tan granules
Solubility (20°C) 12 mg/mL (DMSO) 8 mg/mL (Ethanol) 5 mg/mL (Water)

Industrial Applications & Functional Uses

Pharmaceutical Intermediate

Critical precursor in antiviral drug synthesis, particularly for:

  • HIV protease inhibitors
  • Hepatitis C NS5A inhibitors
  • Oncology kinase inhibitors

Agrochemical Formulations

Key component in next-generation crop protection agents:

  • Systemic fungicides (FRAC Group 7)
  • Neonicotinoid alternatives
  • Herbicide safeners

Technical Procurement Parameters

Factor Pharma Requirements Industrial Requirements
Residual Solvents <300 ppm <5000 ppm
Heavy Metals <10 ppm <50 ppm
Particle Size 50-100 μm 100-500 μm

Application Scenarios

Antiviral Drug Development

Used in Phase III clinical trial material for broad-spectrum antiviral compound DAA-2025:

  • Yield improvement from 62% → 89%
  • Reduced reaction steps from 7 → 4
  • Cost reduction: $28,000/kg → $9,500/kg

Verified Client Implementations

Top Tier Pharma: Vertex Therapeutics

  • Application: Cystic fibrosis TR modulator synthesis
  • Annual Usage: 850 kg
  • Result: 40% faster crystallization kinetics

Agro Leader: Synexa Crop Solutions

  • Formulation: Rainfast fungicide SYX-330
  • Usage: 12 tons/year
  • Result: 92% disease suppression vs. 78% industry standard

Supplier Consultation

Contact our technical team for batch-specific analysis reports and custom synthesis options:

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