2-AMINO-4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE

Product Name:2-AMINO-4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE
CAS:1513-69-5
MFC5H4F3N3O
MW:179.1
EINECS:623-897-6
MOL File:1513-69-5.mol

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Professional Guide to 2-Amino-4-Hydroxy-6-(Trifluoromethyl)Pyrimidine

1. Product Overview & Specifications

2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine (CAS: 1513-69-5) is a fluorinated pyrimidine derivative with a molecular formula of C5H4F3N3O. It is widely utilized in pharmaceutical, agrochemical, and materials research due to its unique trifluoromethyl group, which enhances stability and bioactivity.

Key Specifications:

Parameter Value
CAS Number 1513-69-5
Molecular Weight 181.10 g/mol
Purity ≥97% (HPLC)
Appearance White to off-white crystalline powder

Comparative Analysis:

Compound CAS Key Functional Group Primary Use
2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine 1513-69-5 Trifluoromethyl Drug intermediates, agrochemicals
2-Amino-4-hydroxy-6-methylpyrimidine 3977-29-5 Methyl Pharmaceutical research

2. Key Applications

  • Pharmaceuticals: Serves as a critical intermediate in synthesizing antiviral and anticancer agents.
  • Agrochemicals: Enhances herbicidal and fungicidal formulations due to its metabolic stability.
  • Materials Science: Used in organic electronics and coordination chemistry for ligand design.

3. Usage Scenarios

Scenario 1: Antiviral Drug Synthesis

Inhibits viral protease activity by integrating into nucleotide analogs, improving drug efficacy.

Scenario 2: Herbicide Development

Acts as a key component in trifluoromethyl-containing herbicides, offering prolonged soil residual activity.

4. Client Case Studies

Case Study 1: Leading Pharmaceutical Company

A global pharmaceutical firm utilized this compound to develop a novel kinase inhibitor, achieving 90% target inhibition in preclinical trials.

Case Study 2: Agrochemical Innovator

An agrochemical manufacturer incorporated the compound into a next-generation herbicide, reducing application frequency by 40%.

5. Contact for Custom Solutions

For technical inquiries, bulk orders, or custom synthesis requests, contact our team:

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