Professional Guide to 2-Amino-4-Hydroxy-6-(Trifluoromethyl)Pyrimidine
Table of Contents
1. Product Overview & Specifications
2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine (CAS: 1513-69-5) is a fluorinated pyrimidine derivative with a molecular formula of C5H4F3N3O. It is widely utilized in pharmaceutical, agrochemical, and materials research due to its unique trifluoromethyl group, which enhances stability and bioactivity.
Key Specifications:
| Parameter | Value |
|---|---|
| CAS Number | 1513-69-5 |
| Molecular Weight | 181.10 g/mol |
| Purity | ≥97% (HPLC) |
| Appearance | White to off-white crystalline powder |
Comparative Analysis:
| Compound | CAS | Key Functional Group | Primary Use |
|---|---|---|---|
| 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine | 1513-69-5 | Trifluoromethyl | Drug intermediates, agrochemicals |
| 2-Amino-4-hydroxy-6-methylpyrimidine | 3977-29-5 | Methyl | Pharmaceutical research |
2. Key Applications
- Pharmaceuticals: Serves as a critical intermediate in synthesizing antiviral and anticancer agents.
- Agrochemicals: Enhances herbicidal and fungicidal formulations due to its metabolic stability.
- Materials Science: Used in organic electronics and coordination chemistry for ligand design.
3. Usage Scenarios
Scenario 1: Antiviral Drug Synthesis
Inhibits viral protease activity by integrating into nucleotide analogs, improving drug efficacy.
Scenario 2: Herbicide Development
Acts as a key component in trifluoromethyl-containing herbicides, offering prolonged soil residual activity.
4. Client Case Studies
Case Study 1: Leading Pharmaceutical Company
A global pharmaceutical firm utilized this compound to develop a novel kinase inhibitor, achieving 90% target inhibition in preclinical trials.
Case Study 2: Agrochemical Innovator
An agrochemical manufacturer incorporated the compound into a next-generation herbicide, reducing application frequency by 40%.
5. Contact for Custom Solutions
For technical inquiries, bulk orders, or custom synthesis requests, contact our team:
- Email: info@vivalr.com
- Phone: (86) 15866781826


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