1. Product Overview and Technical Specifications

Key Advantages: Enhanced thermal stability compared to similar nitro-picoline derivatives, making it ideal for high-temperature reactions.

2. Key Applications of 2-Methoxy-3-nitro-6-picoline

Pharmaceutical Intermediate

Critical precursor in synthesizing kinase inhibitors and anti-tumor agents. The methoxy group enables precise molecular orientation during coupling reactions.

Agrochemical Production

Used in next-generation herbicides due to its electron-deficient aromatic ring structure, which enhances binding with plant enzyme targets.

3. Usage Guidelines and Best Practices

Handling Protocol

1. Always use nitrogen atmosphere during transfer
2. Limit exposure to UV light
3. Optimal reaction concentration: 0.5-2.0M

Reaction Optimization

For Buchwald-Hartwig amination: Use Pd(dba)₂ catalyst at 80°C for maximum yield (>85%).

4. Industry Case Studies

Case 1: Antiviral Drug Synthesis

Challenge: Achieve >90% regioselectivity in nucleophilic substitution.
Solution: Used 2-methoxy-3-nitro-6-picoline as directing group.
Result: 92% yield with 95:5 regiomeric ratio.

5. Client Success Stories

PharmaTech Solutions (Germany)

“Using 2-methoxy-3-nitro-6-picoline reduced our API synthesis steps from 14 to 9, cutting production costs by 35%.”

AgroChem Innovations (USA)

“Achieved 40% faster herbicidal activity onset in field tests through improved molecular formulation.”

6. Request a Quote or Technical Consultation

Contact our chemistry experts for:

• Custom synthesis scale-up plans
• Regulatory documentation support
• Bulk pricing (50kg+ orders)

Email: info@vivalr.com
Phone: (86) 15866781826