8-Chloroisoquinoline Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications
- 3. Usage Scenarios
- 4. Client Case Studies
- 5. Inquiry & Contact
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 34784-07-1 |
| Molecular Formula | C9H6ClN |
| Molecular Weight | 163.61 g/mol |
| Purity | ≥98% |
| Appearance | Off-white to light yellow crystalline powder |
| Storage | 2-8°C in airtight container |
Comparative Analysis
| Variant | CAS Number | Key Difference |
|---|---|---|
| 5-Chloroisoquinoline | 5430-45-5 | Chlorine position at C5 |
| 4-Bromo-8-chloroisoquinoline | 1215767-86-4 | Bromine substitution at C4 |
2. Key Applications
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors and neuroprotective agents. Enables precise molecular modifications in drug discovery pipelines.
Organic Synthesis
Essential precursor for cross-coupling reactions (e.g., Suzuki-Miyaura). Serves as ligand in catalytic systems for asymmetric synthesis.
Material Science
Building block for photoactive coordination polymers and OLED components.
3. Usage Scenarios
Scenario 1: Anticancer Drug Development
Used as core structure in tyrosine kinase inhibitor R&D programs. Demonstrated 72% yield improvement in lead optimization stages.
Scenario 2: Asymmetric Catalysis
Modified derivatives achieve 95% enantiomeric excess in chiral amine synthesis.
4. Client Case Studies
Case Study 1: European Pharma Leader
Client leveraged 8-chloroisoquinoline to accelerate development of third-generation EGFR inhibitors, reducing synthesis steps from 14 to 9.
Case Study 2: Asian CRO
Implemented batch-scale production (50kg/mo) for Alzheimer’s drug candidates, maintaining 99.2% purity throughout 18-month collaboration.
5. Inquiry & Contact
Request custom synthesis options or bulk pricing:
| Contact Method | Details |
|---|---|
| info@vivalr.com | |
| Phone | (86) 15866781826 |
Submit technical requirements for tailored solutions. Our team responds within 2 business hours.


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