4-Amino-2-fluoropyridine: Comprehensive Guide for Buyers and Researchers
Table of Contents
- Product Overview & Specifications
- Key Applications
- Industry Case Studies
- Client Success Stories
- Contact for Custom Solutions
Product Overview & Specifications
CAS Number: 3746-65-0
Molecular Formula: C5H5FN2
Molecular Weight: 112.11 g/mol
Appearance: White to off-white crystalline powder
Parameter Comparison Table
| Parameter | 4-Amino-2-fluoropyridine | 2-Fluoropyridine | 4-Aminopyridine |
|---|---|---|---|
| Reactivity | High (amino + fluorine groups) | Moderate | Moderate |
| Pharma Compatibility | Excellent | Good | Limited |
| Typical Purity | ≥98% | ≥95% | ≥97% |
Key Applications
Pharmaceutical Intermediate
Used in synthesis of kinase inhibitors (e.g., EGFR inhibitors) and antiviral agents.
Agrochemical Building Block
Critical component in neonicotinoid-like insecticides and fungicides.
Chemical Research
Ligand in catalytic systems and precursor for fluorinated polymers.
Industry Case Studies
Case 1: Anticancer Drug Development
A biotech company utilized 4-amino-2-fluoropyridine to create third-generation BTK inhibitors, achieving 40% higher selectivity than previous analogs.
Case 2: Crop Protection Formulation
European agrochemical manufacturer reduced environmental persistence by 25% while maintaining efficacy through fluorine substitution.
Client Success Stories
PharmaTech Inc. (USA)
Challenge: Needed low-impurity intermediate for FDA-submission batch
Solution: Custom synthesis at 99.3% purity with strict metal control
Outcome: Accelerated IND approval by 8 months
AgroChem Solutions (India)
Challenge: Develop cost-effective alternative to patented insecticide
Solution: Optimized fluoropyridine-based synthesis pathway
Outcome: 18% production cost reduction vs. traditional methods
Contact for Custom Solutions
Email: info@vivalr.com
Phone: (86) 15866781826
Request:
- Custom purity (95%-99.9%)
- Bulk pricing (1kg to ton-scale)
- Regulatory support (REACH, GLP documentation)


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