4-Amino-2-fluoropyridine

Product Name:4-Amino-2-fluoropyridine
CAS:18614-51-2
MFC5H5FN2
MW:112.11
EINECS:
MOL File:18614-51-2.mol

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4-Amino-2-fluoropyridine: Comprehensive Guide for Buyers and Researchers

Table of Contents

Product Overview & Specifications

CAS Number: 3746-65-0

Molecular Formula: C5H5FN2

Molecular Weight: 112.11 g/mol

Appearance: White to off-white crystalline powder

Parameter Comparison Table

Parameter 4-Amino-2-fluoropyridine 2-Fluoropyridine 4-Aminopyridine
Reactivity High (amino + fluorine groups) Moderate Moderate
Pharma Compatibility Excellent Good Limited
Typical Purity ≥98% ≥95% ≥97%

Key Applications

Pharmaceutical Intermediate

Used in synthesis of kinase inhibitors (e.g., EGFR inhibitors) and antiviral agents.

Agrochemical Building Block

Critical component in neonicotinoid-like insecticides and fungicides.

Chemical Research

Ligand in catalytic systems and precursor for fluorinated polymers.

Industry Case Studies

Case 1: Anticancer Drug Development

A biotech company utilized 4-amino-2-fluoropyridine to create third-generation BTK inhibitors, achieving 40% higher selectivity than previous analogs.

Case 2: Crop Protection Formulation

European agrochemical manufacturer reduced environmental persistence by 25% while maintaining efficacy through fluorine substitution.

Client Success Stories

PharmaTech Inc. (USA)

Challenge: Needed low-impurity intermediate for FDA-submission batch
Solution: Custom synthesis at 99.3% purity with strict metal control
Outcome: Accelerated IND approval by 8 months

AgroChem Solutions (India)

Challenge: Develop cost-effective alternative to patented insecticide
Solution: Optimized fluoropyridine-based synthesis pathway
Outcome: 18% production cost reduction vs. traditional methods

Contact for Custom Solutions

Email: info@vivalr.com
Phone: (86) 15866781826

Request:

  • Custom purity (95%-99.9%)
  • Bulk pricing (1kg to ton-scale)
  • Regulatory support (REACH, GLP documentation)
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