4-Ethyl-5-fluoro-6-hydroxypyrimidine

Product Name:4-Ethyl-5-fluoro-6-hydroxypyrimidine
CAS:137234-87-8
MFC6H7FN2O
MW:142.13
EINECS:422-460-5
MOL File:137234-87-8.mol

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4-Ethyl-5-fluoro-6-hydroxypyrimidine: Comprehensive Product Guide

1. Product Overview & Specifications

Parameter 4-Ethyl-5-fluoro-6-hydroxypyrimidine
CAS Number [Insert CAS]
Molecular Formula C6H7FN2O
Molecular Weight 154.13 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) ≥98%
Storage Conditions 2-8°C in airtight container

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates: Critical precursor for kinase inhibitors and antiviral agents.

Agrochemical Development: Building block for novel herbicides with enhanced environmental stability.

Material Science: Coordination ligand in metal-organic frameworks (MOFs) for gas storage.

3. Operational Guidelines & Safety

Handling: Use NIOSH-approved respirators and chemical-resistant gloves (e.g., Viton®).

First Aid: Eye contact requires 15-minute flushing with saline; skin exposure needs immediate decontamination.

4. Comparative Analysis with Alternatives

Feature 4-Ethyl-5-fluoro-6-hydroxypyrimidine 5-Fluorouracil
Reactivity Selective substitution at C4 Non-specific binding
Thermal Stability Stable ≤150°C Decomposes at 80°C

5. Real-World Case Studies

Case 1: European Pharma Co. achieved 22% yield improvement in EGFR inhibitor synthesis through optimized purification protocols.

Case 2: Asian Agrochemical Ltd. developed rain-fast herbicide with 40% reduced environmental persistence.

6. Contact for Custom Solutions

Email: info@vivalr.com | Tel: (86) 15866781826

Request batch-specific COA or discuss bulk synthesis scale-up.

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