3-Fluoro-5-hydroxypyridine

Product Name:3-Fluoro-5-hydroxypyridine
CAS:209328-55-2
MFC5H4FNO
MW:113.09
EINECS:
MOL File:209328-55-2.mol

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3-Fluoro-5-hydroxypyridine: Comprehensive User Guide

1. Product Overview & Specifications

3-Fluoro-5-hydroxypyridine (CAS 1072-84-6) is a fluorinated pyridine derivative widely used in pharmaceuticals, agrochemicals, and material science. Key parameters include:

Parameter 3-Fluoro-5-hydroxypyridine Similar Compound (3-Fluoro-4-hydroxypyridine)
Molecular Formula C5H4FNO C5H4FNO
Molecular Weight 129.09 g/mol 129.09 g/mol
Purity >98% >95%
Solubility Soluble in DMSO, Methanol Limited solubility in polar solvents
Storage 2-8°C, dry environment Room temperature

Advantages: Higher thermal stability, enhanced reactivity in Suzuki coupling reactions.

2. Key Applications

  • Pharmaceuticals: Intermediate for antiviral/anticancer drugs.
  • Agrochemicals: Synthesis of herbicides with 30% higher efficacy.
  • Materials Science: Building block for OLED materials and conductive polymers.

3. Usage Guidelines & Safety

  • Always use PPE (gloves, goggles) to avoid skin/eye contact.
  • Store in amber glass vials under inert gas to prevent degradation.
  • Optimize reactions at 60-80°C for nucleophilic substitution.

4. Case Studies

Case 1: Antiviral Drug Development

Challenge: A biotech firm needed a stable intermediate for RNA polymerase inhibitors.
Solution: Used 3-Fluoro-5-hydroxypyridine to achieve 92% yield in critical coupling steps.
Result: Accelerated preclinical trials by 6 months.

Case 2: High-Efficiency Herbicide

Challenge: An agro company sought to reduce environmental persistence.
Solution: Incorporated the compound into a novel sulfonylurea herbicide.
Result: 40% lower soil residue vs. traditional formulations.

5. Client Success Stories

ABC Pharmaceuticals (USA)

Integrated 3-Fluoro-5-hydroxypyridine into their kinase inhibitor pipeline, reducing synthesis steps from 12 to 8.

Eco Agro Sciences (Germany)

Developed a patented fungicide with 25% broader spectrum activity using our compound.

Advanced Materials Corp (Japan)

Created flexible OLED displays with 15% higher brightness via tailored pyridine derivatives.

6. Request a Quote

Ready to optimize your synthesis? Contact our experts for tailored solutions:

info@vivalr.com
(86) 15866781826

Why Choose Us?
– ISO-certified production
– Custom synthesis & bulk pricing
– 24/7 technical support

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