2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine (CAS 158515-73-2) is a halogenated pyridine derivative widely used in pharmaceuticals, agrochemicals, and material science. Key parameters:
| Parameter | Specification |
|---|---|
| Molecular Formula | C7H4F3N2O3 |
| Molecular Weight | 238.11 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | Off-white crystalline powder |
| Solubility | Soluble in DMSO, DMF; slightly soluble in water |
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesis of kinase inhibitors and antiviral agents due to its electron-withdrawing trifluoromethyl group.
Agrochemical Precursors
Key component in next-generation herbicides and fungicides with enhanced environmental stability.
Material Science
Building block for OLED materials and liquid crystal displays (LCDs).
3. Comparative Analysis with Analogues
| Compound | Reactivity | Thermal Stability | Cost Efficiency |
|---|---|---|---|
| 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine | High | Up to 250°C | ★★★★☆ |
| 3-Trifluoromethylpyridine | Moderate | 200°C | ★★★☆☆ |
| 5-Nitropyridine-2-ol | Low | 180°C | ★★☆☆☆ |
4. Industry Case Studies
Case 1: ABC Pharma (USA)
Used in scale-up synthesis of JAK3 inhibitor candidates, achieving 92% yield improvement over previous intermediates.
Case 2: AgroGuard Solutions (Germany)
Developed low-residue fungicide formulation with 40% reduced environmental persistence compared to market alternatives.
Case 3: TechMaterials Co., Ltd (China)
Enhanced OLED device lifespan by 15% through optimized electron-transport layer design.
5. Technical Support & Inquiry
Request custom synthesis, bulk pricing, or SDS documentation:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Our technical team responds within 2 business hours with:
- Batch-specific COA
- Regulatory compliance data
- Custom synthesis feasibility reports
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