2-Bromo-1-ethylpyridinium tetrafluoroborate

Comprehensive Guide to 2-Bromo-1-ethylpyridinium Tetrafluoroborate

Table of Contents

• 1. Product Overview & Key Parameters
• 2. Applications & Industrial Uses
• 3. Operational Guidelines & Safety
• 4. Comparative Analysis with Alternatives
• 5. Client Case Studies
• 6. Procurement & Inquiry

1. Product Overview & Key Parameters

2-Bromo-1-ethylpyridinium Tetrafluoroborate (CAS 65442-31-3) is a highly reactive alkylation agent widely used in organic synthesis.

2. Applications & Industrial Uses

Primary applications include:

• Peptide synthesis activation
• Preparation of ionic liquids
• Catalyst in nucleophilic substitutions
• Intermediate in pharmaceutical APIs

3. Operational Guidelines & Safety

Typical Reaction Protocol:

1. Dissolve 1.0 mmol substrate in anhydrous DMF
2. Add 1.2 mmol 2-Bromo-1-ethylpyridinium tetrafluoroborate
3. Stir at 25°C under N₂ for 2-4 hours
4. Quench with ice water and extract with EtOAc

Safety: Use PPE and handle in fume hood due to lachrymatory properties.

4. Comparative Analysis with Alternatives

5. Client Case Studies

Case 1: PharmaTech Inc. (USA) achieved 92% yield in atorvastatin intermediate synthesis using this reagent, reducing reaction time by 40% compared to traditional methods.

Case 2: EuroChem Research utilized it in ionic liquid production, achieving 99.5% conductivity purity for battery electrolyte applications.

6. Procurement & Inquiry

Request quotation or technical support:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Our team provides:

• Bulk pricing (1kg to ton-scale)
• Custom synthesis services
• Regulatory documentation support