3,5-Dibromo-2-hydroxypyridine: Comprehensive Product Guide

1. Product Overview & Specifications

2. Key Applications

3,5-Dibromo-2-hydroxypyridine is widely used in:

• Pharmaceutical intermediates for kinase inhibitors
• Catalyst in cross-coupling reactions
• Ligand in metal-organic frameworks (MOFs)
• Precursor for agrochemical synthesis

3. Usage Guidelines

Safety Precautions

• Use PPE (gloves, goggles) during handling
• Store in airtight containers at 2-8°C

Optimized Reaction Conditions

• Suzuki coupling: 1.5 eq. reagent, 80°C, N₂ atmosphere
• Solubility: 25 mg/mL in DMF or THF

4. Application Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

Used in 6-step synthesis of Bruton’s tyrosine kinase (BTK) inhibitor, achieving 88% yield at final step.

Case 2: MOF Development

Created luminescent Zn-based MOF with 40% increased stability compared to traditional ligands.

5. Client Success Stories

PharmaCo Ltd. (Shanghai)

“Reduced production costs by 18% through improved coupling efficiency in API manufacturing.”

EuroChem Research

“Achieved 99.2% purity in anti-cancer compound synthesis using your brominated pyridine derivative.”

6. Request a Quote

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Tel: (86) 15866781826

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• ISO 9001-certified production
• Bulk order discounts available
• Technical support team with 15+ years experience