Isonicotinamide

Isonicotinamide Product Guide

Table of Contents

• Product Overview & Specifications
• Applications & Industrial Uses
• Usage Guidelines
• Case Studies
• Client Success Stories
• Inquire Now

Product Overview & Specifications

Isonicotinamide (CAS 1453-82-3), a derivative of nicotinamide, is widely used in pharmaceuticals, agrochemicals, and organic synthesis. Below are key specifications:

Applications & Industrial Uses

Key Applications:

• Pharmaceuticals: Intermediate for antitubercular drugs (e.g., Isoniazid derivatives).
• Coordination Chemistry: Ligand in metal-organic frameworks (MOFs).
• Agrochemicals: Precursor for fungicides and herbicides.
• Research: Used in biochemical studies targeting NAD+ metabolism.

Usage Guidelines

Recommended Protocols:

• Synthesis: Use 1:1 molar ratio with metal ions for MOF preparation at 80°C.
• Drug Formulation: Blend with excipients under inert gas to prevent oxidation.
• Safety: Wear PPE; avoid inhalation/contact with skin. LD50 (oral, rat): 1200 mg/kg.

Case Studies

Case 1: Antifungal Agent Development

• Client: European Agrochemical Company
• Objective: Develop a low-toxicity fungicide for citrus crops.
• Solution: Formulated isonicotinamide-based compound (0.05% w/v) with 94% efficacy against Penicillium spp.

Case 2: Tuberculosis Drug Intermediate

• Client: Indian Pharma Manufacturer
• Challenge: Improve yield of isoniazid precursor.
• Result: Optimized reaction conditions increased yield from 72% to 89%.

Client Success Stories

1. ABC Pharmaceuticals (USA)

• Project: Scalable synthesis of isonicotinamide for Phase III clinical trials.
• Outcome: Delivered 500 kg/month of 99.7% pure product, reducing API costs by 18%.

2. ChemCo Ltd. (Germany)

• Application: MOF production for CO2 capture.
• Benefit: Achieved 12% higher adsorption capacity vs. traditional ligands.

3. AgroGreen Solutions (Brazil)

• Use Case: Antifungal treatment for soybean storage.
• Result: Reduced post-harvest losses by 22% in pilot trials.

Inquire Now

Request a quote or technical dossier:

• Email: info@vivalr.com
• Phone: (86) 15866781826

Customization Options: Bulk pricing, HPLC/GCMS reports, and regulatory support available.